DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9684 and Smyd1

DIOPT Version :9

Sequence 1:	NP_649797.2	Gene:	CG9684 / 41000	FlyBaseID:	FBgn0037583	Length:	642	Species:	Drosophila melanogaster
Sequence 2:	NP_001100065.1	Gene:	Smyd1 / 297333	RGDID:	1305105	Length:	490	Species:	Rattus norvegicus

Alignment Length:	500	Identity:	98/500 - (19%)
Similarity:	174/500 - (34%)	Gaps:	137/500 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 CVHCANAAERVCQRCGD----FYCSKHCQRQDWLRHRYICIPLPALVS-PNE------YSVFQSD 73
            |..|....||: .|||.    .||.:.||:..||.|:..|..:..... |||      ..:::.:
  Rat    52 CHTCFKRQERL-HRCGQCKFAHYCDRTCQKDAWLNHKNECSAIKRYGKVPNENIRLAARIMWRVE 115

  Fly    74 REST-LEGACSLNADKSVVEASPIPLSRSPILPDLQ--CNNAGRSSIIAAKDDIPVS----PPKA 131
            ||.| |...|.::.|                  |||  ..:.|.......:.|:...    ||::
  Rat   116 REGTGLTEGCLVSVD------------------DLQNHVEHFGEEEQKELRVDVDTFLQYWPPQS 162

  Fly   132 IIPPSGAMVYITDFISSNRCYIRDASESAERAFDEVCKKVNTIATLLPRI----KNPPPNRLCLV 192
               ...:|.||:.......|  ...:.|.:|....|.      ..:.|.:    .:..||  |.|
  Rat   163 ---QQFSMQYISHIFGVINC--NGFTLSDQRGLQAVG------VGIFPNLGLVNHDCWPN--CTV 214

  Fly   193 HF-NGMY--VRAKMCKKLR-EVSHLFLVDLGIKHSGPFFDFKDINDELKALPCSSQLVQLKNV-- 251
            .| ||.:  |::....::| |:..|..:..|.:.:..:.||..:::|.:.        |||..
  Rat   215 IFNNGNHEAVKSMFHTQMRIELRALGKISEGEELTVSYIDFLHLSEERRQ--------QLKKQYY 271

  Fly   252 --LNCDYSNDVIAFNSKFVGKKYMATIKKCPGLHLVELVNTEMNFSVNEQLNAFFNSKKLLRNPN 314
              .:|::.       .|.:.......:|:.|          :.:..|.:::..|  ||..|...:
  Rat   272 FDCSCEHC-------QKGLKDDLFLAVKEDP----------KPSQEVVKEMTQF--SKDTLEKID 317

  Fly   315 SAA------ENIKSC--SLEGPQPSHIDQPIAIPAI--ECKKMLTKPEVQNECEEI--------- 360
            .|.      |.:|.|  .||..:|...|..:.:..:  ...::|:..:...|....
  Rat   318 KARSEGLYHEVVKLCRECLEKQEPVFADTNLYVLRLLSIVSEVLSYLQAFEEASHYARRMVDGYM 382

  Fly   361 -LKQQNSGQID----QSKSTN-------------------VLVTEGASNKMLGFIDLADKATKTD 401
             |...|:.|:.    ::..||                   :|||.|.|:.:..  ||.....:|:
  Rat   383 KLYHHNNAQLGMAVMRAGLTNWHAGHIEVGHGMICKAYAILLVTHGPSHPITK--DLEAMRMQTE 445

  Fly   402 QDTAPKPKDEDVKHSLTQCLTPKANYPLQLPNHKKNLELPVI-HK 445
            .:.....::|.:.|.:.:...  .|.|:|:.....|...|.: ||
  Rat   446 MELRMFRQNEFMYHKMREAAL--NNQPMQVMAEPSNEPAPALFHK 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9684	NP_649797.2	zf-MYND	20..55	CDD:280009	14/38 (37%)
		TUDOR	132..250	CDD:278965	25/125 (20%)
		TUDOR	527..574	CDD:119391
Smyd1	NP_001100065.1	zf-MYND	52..90	CDD:280009	14/38 (37%)
Smyd1	NP_001100065.1	SET	<194..257	CDD:214614	15/70 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	1	0.960