Protein Alignment ARSA and Sgsh

DIOPT Version :9

• Sequence 1: XP_016884289.1
• Gene: ARSA / 410
• HGNCID: 713
• Length: 547
• Species: Homo sapiens
• Sequence 2: NP_650760.1
• Gene: Sgsh / 42266
• FlyBaseID: FBgn0038660
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 542
• Identity: 141/542 - (26%)
• Similarity: 201/542 - (37%)
• Gaps: 172/542 - (31%)

Human    11 LALAAGLAVARPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSR 75
            |.|.||.: |.|.|::|:.|||.|: :.|.|.:....|||||.||..||.|.:.:..||.|:|||
  Fly    10 LWLIAGCS-AGPQNVLLLLADDAGF-ESGAYLNKFCQTPNLDALAKRGLLFNNAFTSVSSCSPSR 72

Human    76 AALLTGRLPVRMGMY---PGV----LVPSSRGGLP--LEEVTVAEVLAARGYLTGMAGKWHLGVG 131
            :.||||:.....|||   .||    ::|.: |.||  :.:.:...:      |:|:.||.|:|..
  Fly    73 SQLLTGQAGHSSGMYGLHQGVHNFNVLPDT-GSLPNLIRDQSGGRI------LSGIIGKKHVGAA 130

Human   132 PEGAFLPPHQGFHRFLGIPYSHDQGPC-QNLTCFPPATPCDGGCDQGLVPIPLLANLSVEAQPPW 195
            ....|        .|......|..... :|:|
  Fly   131 NNFRF--------DFEQTEEQHSINQIGRNIT--------------------------------- 154

Human   196 LPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTH-----YPQFSGQSFAERSGRGPFG----- 250
                  |...:|...:..|:.:.:||||....|..|     .|||.  .|.||.|.|..|
  Fly   155 ------RMKEYARQFLKQAKDEKKPFFLMVGFHDPHRCGHITPQFG--EFCERWGSGEEGMGSIP 211

Human   251 --------------------------------DSLMELDAAVGTLMTAIGDLGLLEETLVIFTAD 283
                                            .::..||..||.::..:...|:.::||||:|:|
  Fly   212 DWKPIYYDWRNLDVPAWLPDTDVVRQELAAQYMTISRLDQGVGLMLKELEAAGVADQTLVIYTSD 276

Human   284 NGPETMRMSRGGCSGLLRCGKGTTYEGGVREPALAFWPG-----HIAPGVTHELASSLDLLPTLA 343
            |||.    ..||.:.|        ||.|:|.|.:...|.     |.|   |..:.|.||:.|::.
  Fly   277 NGPP----FPGGRTNL--------YEHGIRSPLIISSPNKEDRHHEA---TAAMVSLLDIYPSVM 326

Human   344 ALAGAPLPNVT-LDGFDLSPLLLGTGKSP----RQSLFFYPSYPDEVRGVF---AVRTGKYK-AH 399
            .....|.||.| :.|..:.|:|   .:.|    ..|:|...|| .||...:   .||..:|| .|
  Fly   327 DALQIPRPNDTKIVGRSILPVL---REEPPIKESDSVFGSHSY-HEVTMAYPMRMVRNRRYKLIH 387

Human   400 FFTQGNPSPWIPPP---DLLTPPRSPRSLAPPLALALCTELAPSPGSAHSDTTADPACHASSSLT 461
                 |.:.|...|   |..|.|    :....|...|..:..|               ...|.|.
  Fly   388 -----NINYWADFPIDQDFYTSP----TFQQILNATLRKQTLP---------------WYRSLLQ 428

Human   462 AHEPP--LLYDLSKDPGENYNL 481
            .::.|  .|||:..||.|.:||
  Fly   429 YYQRPEWELYDIKTDPLERFNL 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARSA	XP_016884289.1	None
Sgsh	NP_650760.1	AslA	17..476	CDD:225661	137/535 (26%)
		SGSH	22..471	CDD:293751	135/529 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810