Protein Alignment ARSA and CG18278

DIOPT Version :10

• Sequence 1: NP_000478.3
• Gene: ARSA / 410
• HGNCID: 713
• Length: 509
• Species: Homo sapiens
• Sequence 2: NP_725289.1
• Gene: CG18278 / 36487
• FlyBaseID: FBgn0033836
• Length: 492
• Species: Drosophila melanogaster
• Alignment Length: 516
• Identity: 130/516 - (25%)
• Similarity: 179/516 - (34%)
• Gaps: 143/516 - (27%)

Human     9 LLLALAAGLAVARPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTP 73
            |:||.....|..:.|||:||.:||......|.:  |...|  ::.|..||..|.:.|.|..:|.|
  Fly    10 LVLACLGNTASEKLPNILLILSDDQDVELRGMF--PMEHT--IEMLGFGGALFHNAYTPSPICCP 70

Human    74 SRAALLTGRLPVRMGMYP---GVLVPSSRGGL-------PLEEVTVAEVLAARGYLTGMAGK--- 125
            :|.:|||       |||.   |....|..||.       .||...:..:|...||.|...||
  Fly    71 ARTSLLT-------GMYAHNHGTRNNSVSGGCYGPHWRRALEPRALPYILQQHGYNTFFGGKYLN 128

Human   126 --WHLGVGPEGAFLPPHQGFHRFLGIPYSHDQGPCQNLTCFPPATPCDGGCDQGLVPIPLLANL- 187
              |..|..|        :|::.|.|:   |......|.|                    |..|.
  Fly   129 QYWGAGDVP--------KGWNHFYGL---HGNSRYYNYT--------------------LRENSG 162

Human   188 SVEAQPPWLPGLEARYMAFAHDLMADAQRQDRPFFLYYASHHTHYP---------QFS------G 237
            :|..:..:|..|   ....|.|.:.:|.:...|||...|....|.|         .||      .
  Fly   163 NVHYESTYLTDL---LRDRAADFLRNATQSSEPFFAMVAPPAAHEPFTPAPRHEGVFSHIEALRT 224

Human   238 QSFAE---------RSGR--------------GPFGDSLMELDAAVGTLMTAIGDLGLLEETLVI 279
            .||.:         |:.|              ....::|:.:|..|.|||..:.|...||.|.:|
  Fly   225 PSFNQVKQDKHWLVRAARRLPNETINTIDTYFQKRWETLLAVDELVVTLMGVLNDTQSLENTYII 289

Human   280 FTADNGPETMRMSRGGCSGLLRCGKGTTYEGGVREPALAFWPGHIAPGVTHELASSL-DLLPTLA 343
            :|:|||....:.::       ...|...||..:..|.|...|| |||....:.|.|| ||.||:.
  Fly   290 YTSDNGYHVGQFAQ-------PFDKRQPYETDINVPLLIRGPG-IAPESHIDTAVSLVDLAPTIL 346

Human   344 ALAGAPLPNVTLDGFDLSPLLLGTGKSPRQSLFFYPSYPDEVRGVFAVRTGKYKAHFFTQGSAHS 408
            |.|....|:. :||.....|||   ...|:..||..|...|..|...:.|...:..:     ...
  Fly   347 AWADIDTPSY-MDGQSFHELLL---NKRRRVPFFERSLLIEYWGEGTLATFNPECPW-----PEK 402

Human   409 DTTAD--PA--CHASSSLT---------AHEPPLL-------------YDLSKDPGENYNL 443
            |..|.  ||  ||...:..         .|....:             |||..||.:..|:
  Fly   403 DRLAQCTPAADCHCQDAWNNTYACLRNIRHREDRIYCEFRDNENFLEAYDLQLDPFQMTNI 463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARSA	NP_000478.3	ARSA	22..505	CDD:293777	126/503 (25%)
CG18278	NP_725289.1	G6S	24..467	CDD:293766	126/502 (25%)