Protein Alignment ARSA and CG32191

DIOPT Version :10

• Sequence 1: NP_000478.3
• Gene: ARSA / 410
• HGNCID: 713
• Length: 509
• Species: Homo sapiens
• Sequence 2: NP_730304.2
• Gene: CG32191 / 317903
• FlyBaseID: FBgn0052191
• Length: 564
• Species: Drosophila melanogaster
• Alignment Length: 560
• Identity: 159/560 - (28%)
• Similarity: 227/560 - (40%)
• Gaps: 128/560 - (22%)

Human    18 AVARPPNIVLIFADDLGYGDLGCYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGR 82
            |.||.|||::|.|||:|:.|:...|.....|||:|.||..|......|.| ::|||||.|||:||
  Fly    22 AAARRPNIIIIMADDMGFDDVSFRGGREFLTPNIDALAYHGRLLDRLYAP-AMCTPSRGALLSGR 85

Human    83 LPVRMGMYPGVLVPSSRGGLPLEEVTVAEVLAARGYLTGMAGKWHLGVG-PEGAFLPPHQGFHRF 146
            .|:..|....|:.......|.|....:.|:....||.|.:.||||||.. ||  :.|..:||...
  Fly    86 YPIHTGTQHFVISNEEPWALTLNATLMPEIFKEAGYSTNLVGKWHLGFSRPE--YTPTRRGFDYH 148

Human   147 LG-----IPY--SHDQGPCQN------------LTCFPPATPCDGGCDQGLVPIPLLANLSVEAQ 192
            .|     |.|  ...:.|..|            |.|          .|:|:....||.
  Fly   149 FGYWGAYIDYFQRRSKMPVANYSLGYDFRRNMELEC----------RDRGVYVTDLLT------- 196

Human   193 PPWLPGLEARYMAFAHDLMADAQRQDRPFFL---YYASHHTH------YPQFSGQSFA--ERSGR 246
                        |.|..|:.|...:::|.||   :.|:|..:      .|:...|.|:  :...|
  Fly   197 ------------AEAERLIKDHADKEQPLFLMLSHLAAHTANEDDPLQAPEEEIQKFSYIKDPNR 249

Human   247 GPFGDSLMELDAAVGTLMTAIGDLGLLEETLVIFTADNG-PETMRMSRGGCSGLLRCGKGTTYEG 310
            ..:...:.:||.:||.::||:.....||.::|||.:||| |.....|..|.:..||..|.|.:||
  Fly   250 RKYAAMISKLDQSVGRIITALSSTDQLENSIVIFYSDNGAPSVGMFSNTGSNFPLRGQKNTPWEG 314

Human   311 GVREPALAFWPGHIAPG-VTHELASSLDLLPTLAALAGAPL-PNVTLDGFDLSPLLLGTGKS--- 370
            |||.....:..|..|.| :..:.....|.||||:..|...| .::.|||.||.|.|.|:..:
  Fly   315 GVRVAGAIWSSGLQARGSIFRQPLYVADWLPTLSRAADIELDSSLKLDGIDLWPELSGSADAPHV 379

Human   371 PRQSLFFYPSYPDEVRGVFAVRTGKYKAHFFTQGSAHSDTT--------ADP-----ACHASSSL 422
            ||:.|...    |:|..:.|::.|::|....|..|...|:.        .||     |....:|.
  Fly   380 PREILHIL----DDVWRLSALQMGQWKYVNGTTASGRYDSVLTYRELDDLDPRDSRYAVTVRNSA 440

Human   423 TAH---------------------------------EPPL---LYDLSKDPGENYNLLGGVAGAT 451
            |:.                                 .|.|   |||:..||.|..||:  .:...
  Fly   441 TSRALSRYDLRRLTQQRISLTRRLAAVRCGDLQRSCNPLLEECLYDILSDPCEQNNLV--YSERH 503

Human   452 PEVLQAL-KQLQLLKAQLDAAVTFGPSQVARGEDPALQIC 490
            .:||.|| :::|.|:|   :|...|........||.|..|
  Fly   504 SDVLTALRRRVQELRA---SASRPGNRASMPEADPTLHTC 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ARSA	NP_000478.3	ARSA	22..505	CDD:293777	156/556 (28%)
CG32191	NP_730304.2	4-S	27..408	CDD:293753	125/416 (30%)