DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stck and RGA1

DIOPT Version :9

Sequence 1:	NP_731242.1	Gene:	stck / 40999	FlyBaseID:	FBgn0020249	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	NP_014770.1	Gene:	RGA1 / 854294	SGDID:	S000005653	Length:	1007	Species:	Saccharomyces cerevisiae

Alignment Length:	188	Identity:	44/188 - (23%)
Similarity:	75/188 - (39%)	Gaps:	30/188 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 CTRCADGFEPTEKIVNSNGELWHTQCFVCAQCFRPFQDGIFYEFEGRKYCERDFHVL-------- 77
            |.||.: |..|........:.|||.||.|.:|.:|..            ||.||.||
Yeast    13 CVRCKE-FITTGHAYELGCDRWHTHCFACYKCEKPLS------------CESDFLVLGTGALICF 64

  Fly    78 -FAPCCNKCGEFV--IGRVIKAMSASWHPQCFRCQLCAKELADCGFIKNQNRALCHECNAKVKAE 139
             .:..|..||:.:  :..::.:.:.::...||:|..|.:.:||..:.|.:....|..|:.|:.|:
Yeast    65 DCSDSCKNCGKKIDDLAIILSSSNEAYCSDCFKCCKCGENIADLRYAKTKRGLFCLSCHEKLLAK 129

  Fly   140 ITGRYVCQKCHGLIDEEPLRFRGEVYHGYHFSCTACGTELDSTAREVKSRPGLAANDM 197
              .:|..:|...|....|......:.:|:....:|.....:.|.    |||....|::
Yeast   130 --RKYYEEKKRRLKKNLPSLPTPVIDNGHTDEVSASAVLPEKTF----SRPASLVNEI 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stck	NP_731242.1	LIM1_PINCH	21..79	CDD:188717	19/66 (29%)
		LIM2_PINCH	82..133	CDD:188718	11/52 (21%)
		LIM3_PINCH	146..206	CDD:188719	10/52 (19%)
		LIM4_PINCH	212..265	CDD:188720
		LIM5_PINCH	273..326	CDD:188721
RGA1	NP_014770.1	LIM1_Rga	13..67	CDD:188780	19/66 (29%)
		LIM2_Rga	70..123	CDD:188781	11/52 (21%)
		Smc	<569..>673	CDD:224117
		RhoGAP	803..1002	CDD:214618
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900