DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stck and RGA2

DIOPT Version :9

Sequence 1:	NP_731242.1	Gene:	stck / 40999	FlyBaseID:	FBgn0020249	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	NP_010667.1	Gene:	RGA2 / 851985	SGDID:	S000002787	Length:	1009	Species:	Saccharomyces cerevisiae

Alignment Length:	169	Identity:	39/169 - (23%)
Similarity:	58/169 - (34%)	Gaps:	55/169 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 QCFVCAQCFRPFQDGIFYEFEGRKYCERDFHVLFAPCCNKCGEFVIGRVIKAMSASWHPQCFRCQ 109
            |..:|.:|.:.......||.|.:|                                ||.|||.|.
Yeast     9 QSSLCVRCNKSIASSQVYELESKK--------------------------------WHDQCFTCY 41

  Fly   110 LCAKEL-ADCGF-IKNQNRALCHECNAKVKAEITGRYVCQKCHGLIDEEP--LRFRGEVYHGYHF 170
            .|.|:| ||..| :.:....:|::|:.|          |..|...||:..  |....|.|....|
Yeast    42 KCDKKLNADSDFLVLDIGTLICYDCSDK----------CTNCGDKIDDTAIILPSSNEAYCSNCF 96

  Fly   171 SCTACGTELDSTAREVKSRPGLAANDMNELYCLRCHDKM 209
            .|..|...: ...:..|::.||.        |:.||:|:
Yeast    97 RCCRCSNRI-KNLKYAKTKRGLC--------CMDCHEKL 126

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stck	NP_731242.1	LIM1_PINCH	21..79	CDD:188717	7/33 (21%)
		LIM2_PINCH	82..133	CDD:188718	13/52 (25%)
		LIM3_PINCH	146..206	CDD:188719	14/61 (23%)
		LIM4_PINCH	212..265	CDD:188720
		LIM5_PINCH	273..326	CDD:188721
RGA2	NP_010667.1	LIM1_Rga	13..67	CDD:188780	19/85 (22%)
		LIM2_Rga	70..123	CDD:188781	14/61 (23%)
		RhoGAP	815..1002	CDD:214618
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900