DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stck and LRG1

DIOPT Version :9

Sequence 1:	NP_731242.1	Gene:	stck / 40999	FlyBaseID:	FBgn0020249	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	NP_010041.2	Gene:	LRG1 / 851358	SGDID:	S000002399	Length:	1017	Species:	Saccharomyces cerevisiae

Alignment Length:	148	Identity:	41/148 - (27%)
Similarity:	62/148 - (41%)	Gaps:	33/148 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   213 ICGACRR---PIEERVVT---ALGKHWHVEHFVCAKCEKPFLGHRHY------EKRGLAYCETHY 265
            ||..|.:   |..:|..|   ||||::|...|.|..|:|| |..:::      ....:..|:..|
Yeast    27 ICARCNKLVIPDSQRTKTTLKALGKYYHESCFTCQDCQKP-LKPKYFPYQVDKTSESILLCQYDY 90

  Fly   266 HQLFGNLCFVCNQVIGGDVFTALNKAWCVHHFACSVCDT------------KMTQKSKFYEYDEK 318
            .:....||.||:..:.|..:||....:...||:|::|.|            ::..|..|.:|..|
Yeast    91 FRRHNLLCHVCDTPLRGLYYTAFGYRYDEEHFSCTICATPCGVKKCFMYGNQLYCKYHFLKYFSK 155

  Fly   319 PVCKKC-------YDRFP 329
            . ||.|       |..||
Yeast   156 R-CKGCEFPISDQYIEFP 172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stck	NP_731242.1	LIM1_PINCH	21..79	CDD:188717
		LIM2_PINCH	82..133	CDD:188718
		LIM3_PINCH	146..206	CDD:188719
		LIM4_PINCH	212..265	CDD:188720	18/63 (29%)
		LIM5_PINCH	273..326	CDD:188721	18/71 (25%)
LRG1	NP_010041.2	LIM1_Lrg1p_like	28..90	CDD:188777	17/62 (27%)
		LIM	98..149	CDD:259829	12/50 (24%)
		LIM3_Lrg1p_like	419..475	CDD:188779
		RhoGAP_fLRG1	728..959	CDD:239862
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
TreeFam	0	0.000	Not matched by this tool.
	3	2.910