DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stck and prickle3

DIOPT Version :9

Sequence 1:	NP_731242.1	Gene:	stck / 40999	FlyBaseID:	FBgn0020249	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	XP_698649.4	Gene:	prickle3 / 570116	ZFINID:	ZDB-GENE-081105-86	Length:	783	Species:	Danio rerio

Alignment Length:	273	Identity:	76/273 - (27%)
Similarity:	103/273 - (37%)	Gaps:	64/273 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 PTEKI--VNSNGELWHTQCFVCAQCFR--PFQDG-----------------IFYEFEGRKYCERD 73
            |.:|:  |||.||.:..:     |...  |..|.                 :|.:...|:...|.
Zfish   112 PEDKVPYVNSPGERYRIK-----QLLHQLPAHDSEPQYCNSLDEEEKKELRLFSQQRKRENLGRG 171

  Fly    74 FHVLF-----APCCNKCGEFVIGRVIKAMSAS-------WHPQCFRCQLCAKELADCGFIKNQNR 126
            ...||     ...|.:||..:.|..| |:.||       ||||||:|..|.:.|.|..:......
Zfish   172 IVRLFPVTMTGAICQQCGRQICGGDI-AVFASRAGHGSCWHPQCFQCASCNELLVDLIYFYQDGH 235

  Fly   127 ALCHECNAKVKAEITGRYVCQKCHGLI-DEEPLRFRGEVYHGYHFSCTACGTELDS---TAREVK 187
            ..|...:|:   .|..|  ||.|..:| .:|.....|..:|..||.|..|...|..   ..||
Zfish   236 IYCGRHHAE---HIKPR--CQACDEIIFADECTEAEGRHWHMKHFCCFECEAALGGQRYIMRE-- 293

  Fly   188 SRPGLAANDMNELYCLRCHDKMGIPICGACRR--PIEERVVTALGKHWHVEH--FVCAKCEKPFL 248
            |||          ||.||::.:....|..|..  .|::..:|..|:|||...  |.||.|..|.|
Zfish   294 SRP----------YCCRCYESLYAEYCDTCGEHIGIDQGQMTYEGQHWHASEQCFCCACCRLPLL 348

  Fly   249 GHRHYEKRGLAYC 261
            |.....:.||.:|
Zfish   349 GRPFLPRGGLIFC 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stck	NP_731242.1	LIM1_PINCH	21..79	CDD:188717	15/74 (20%)
		LIM2_PINCH	82..133	CDD:188718	19/57 (33%)
		LIM3_PINCH	146..206	CDD:188719	20/63 (32%)
		LIM4_PINCH	212..265	CDD:188720	18/54 (33%)
		LIM5_PINCH	273..326	CDD:188721
prickle3	XP_698649.4	PET_Prickle	81..177	CDD:193602	14/69 (20%)
		LIM1_Prickle	185..243	CDD:188799	19/58 (33%)
		LIM2_Prickle	248..303	CDD:188802	22/68 (32%)
		LIM3_Prickle	308..366	CDD:188804	18/54 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910