DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stck and pxnb

DIOPT Version :9

Sequence 1:	NP_731242.1	Gene:	stck / 40999	FlyBaseID:	FBgn0020249	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	XP_021334029.1	Gene:	pxnb / 565130	ZFINID:	ZDB-GENE-130530-697	Length:	1197	Species:	Danio rerio

Alignment Length:	306	Identity:	92/306 - (30%)
Similarity:	127/306 - (41%)	Gaps:	78/306 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 CTRCADGFEP-TEKIVNSNGELWHTQCFVCAQCFRPFQDGIFYEFEGRKYCERDFHVLFAPCCNK 84
            |..|:   :| ..::|.:.|..||.:.|||..|........|:|.||:.|||||:|.||:|.|..
Zfish   964 CGACS---KPIVGQVVTAMGRTWHPEHFVCTHCQEEIGSRNFFEREGQPYCERDYHHLFSPRCYY 1025

  Fly    85 CGEFVIGRVIKAMSASWHPQCFRCQLCAKELADCGFIKNQNRALCHECNAKVKAEITGRYVCQKC 149
            |...::.:|:.|:..:|||:.|.|       |.||
Zfish  1026 CNGPILDKVVTALDRTWHPEHFFC-------AQCG------------------------------ 1053

  Fly   150 HGLIDEEPLRFRGEVYHGYHFSCTACGTELDSTAREVKSRPGLAANDMNELYCLRCHDKMGIPIC 214
                     .|.|.  .|:|        |.|..|                 ||.:.:..:..|.|
Zfish  1054 ---------AFFGP--EGFH--------EKDGKA-----------------YCRKDYFDLFAPKC 1082

  Fly   215 GACRRPIEERVVTALGKHWHVEHFVCAKCEKPFLGHRHYEKRGLAYCETHYHQLFGNLCFVCNQV 279
            |.|.|.|.|..::||...||.|.|||.:|..||:....:|..|..|||.|||...|:||..|.:.
Zfish  1083 GGCARAILENYISALSSLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHARRGSLCSGCQKP 1147

  Fly   280 IGGDVFTALNKAWCVHHFACSVCDTKMTQKSKFYEYDEKPVCKKCY 325
            |.|...||:.|.:...||.|:.| .|...|..|.|.::||.|:.|:
Zfish  1148 ITGRCITAMGKKFHPEHFVCAFC-LKQLNKGTFKEQNDKPYCQGCF 1192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stck	NP_731242.1	LIM1_PINCH	21..79	CDD:188717	22/58 (38%)
		LIM2_PINCH	82..133	CDD:188718	12/50 (24%)
		LIM3_PINCH	146..206	CDD:188719	9/59 (15%)
		LIM4_PINCH	212..265	CDD:188720	23/52 (44%)
		LIM5_PINCH	273..326	CDD:188721	19/53 (36%)
pxnb	XP_021334029.1	Paxillin	96..272	CDD:308898
		Atrophin-1	<178..684	CDD:331285
		LIM1_Paxillin_like	964..1016	CDD:259830	20/54 (37%)
		LIM2_Paxillin_like	1023..1074	CDD:188723	21/123 (17%)
		LIM3_Paxillin_like	1082..1134	CDD:188724	23/51 (45%)
		LIM4_Paxillin	1141..1192	CDD:188795	18/51 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.920