DRSC/TRiP Functional Genomics Resources

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Protein Alignment stck and FBLIM1

DIOPT Version :9

Sequence 1:NP_731242.1 Gene:stck / 40999 FlyBaseID:FBgn0020249 Length:348 Species:Drosophila melanogaster
Sequence 2:NP_001019386.1 Gene:FBLIM1 / 54751 HGNCID:24686 Length:374 Species:Homo sapiens


Alignment Length:200 Identity:55/200 - (27%)
Similarity:76/200 - (38%) Gaps:56/200 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    21 CTRCADGFEPTEKIVNSNGELWHTQCFVCAQCFRPFQDGIFYEFEGRKYCERDFHVLFAPC---- 81
            |..|.....|.|..|.:....:|.|||.|..|.|......||:.:||..||        ||    
Human   183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCE--------PCYQDT 239

  Fly    82 ---CNKCGEFVIGRVIKAMSASWHPQCFRCQLCAKELADCGF-IKNQNRALCHECNAKVKAEITG 142
               |.||||.|...:|:|:..::||.||.|..||:.:.|..| :.:||...|             
Human   240 LERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYC------------- 291

  Fly   143 RYVCQKCHGLIDEEPLRFRGEVYHGYHFS-CT--ACGTELD-STAREVKSRPGLAANDMNELYCL 203
                      :|:         ::.|... ||  ..||..| |..:|:...||..|    .:.||
Human   292 ----------LDD---------FYRYEKGLCTGWGAGTGRDPSRVKELSLSPGCWA----RVSCL 333

  Fly   204 RCHDK 208
            ..:.|
Human   334 LVYYK 338

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
stckNP_731242.1 LIM1_PINCH 21..79 CDD:188717 18/57 (32%)
LIM2_PINCH 82..133 CDD:188718 20/51 (39%)
LIM3_PINCH 146..206 CDD:188719 14/63 (22%)
LIM4_PINCH 212..265 CDD:188720
LIM5_PINCH 273..326 CDD:188721
FBLIM1NP_001019386.1 Filamin-binding 1..70
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 41..119
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 135..176
LIM 183..236 CDD:259829 19/60 (32%)
LIM2_FBLP-1 243..295 CDD:188758 21/83 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1704
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X39
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.810

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