DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stck and LMO7

DIOPT Version :9

Sequence 1:	NP_731242.1	Gene:	stck / 40999	FlyBaseID:	FBgn0020249	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	XP_024305122.1	Gene:	LMO7 / 4008	HGNCID:	6646	Length:	1727	Species:	Homo sapiens

Alignment Length:	109	Identity:	28/109 - (25%)
Similarity:	46/109 - (42%)	Gaps:	36/109 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   140 ITGRYVCQKCHGLIDE------EPLRFRGEVYHGYHFSCTACGTEL--DSTAREVKSRPGLAAND 196
            ::|:.:|..|:.::.:      |.|   |..||.:.|.|.||..:|  .|:..||:.|
Human  1636 VSGKRICSYCNNILGKGAAMIIESL---GLCYHLHCFKCVACECDLGGSSSGAEVRIR------- 1690

  Fly   197 MNELYCLRCHDKMGIPICGACRR--------PIEERVVTALGKH 232
            .::|||..|:.:.      .|:|        |.:|    |.|.|
Human  1691 NHQLYCNDCYLRF------KCKRANQRENFLPFKE----ATGSH 1724

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stck	NP_731242.1	LIM1_PINCH	21..79	CDD:188717
		LIM2_PINCH	82..133	CDD:188718
		LIM3_PINCH	146..206	CDD:188719	19/67 (28%)
		LIM4_PINCH	212..265	CDD:188720	7/29 (24%)
		LIM5_PINCH	273..326	CDD:188721
LMO7	XP_024305122.1	DUF4757	213..>263	CDD:318215
		DUF4757	627..774	CDD:318215
		PDZ	1042..1109	CDD:238080
		GBP_C	<1255..1311	CDD:328214
		Neuromodulin_N	<1256..1414	CDD:331332
		coiled coil	1298..1309	CDD:293879
		LIM	1642..1700	CDD:259829	19/67 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900