DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stck and pxna

DIOPT Version :9

Sequence 1:	NP_731242.1	Gene:	stck / 40999	FlyBaseID:	FBgn0020249	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	NP_963882.1	Gene:	pxna / 399546	ZFINID:	ZDB-GENE-040105-1	Length:	533	Species:	Danio rerio

Alignment Length:	293	Identity:	83/293 - (28%)
Similarity:	120/293 - (40%)	Gaps:	74/293 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 KIVNSNGELWHTQCFVCAQCFRPFQDGIFYEFEGRKYCERDFHVLFAPCCNKCGEFVIGRVIKAM 97
            ::|.:.|..||.:.|||.||........|:|.:|:.|||:|:|.||:|.|..|...::.:|:.|:
Zfish   310 QVVTAMGRTWHPEHFVCTQCQEEIGSRNFFERDGQPYCEKDYHSLFSPRCYYCSGPILDKVVTAL 374

  Fly    98 SASWHPQCFRCQLCAKELADCGFIKNQNRALCHECNAKVKAEITGRYVCQKCHGLIDEEPLRFRG 162
            ..:|||:.|.|..|.......||.:.:.:|
Zfish   375 DKTWHPEHFFCAQCGSFFGPEGFHEKEGKA----------------------------------- 404

  Fly   163 EVYHGYHFSCTACGTELDSTAREVKSRPGLAANDMNELYCLRCHDKMGIPICGACRRPIEERVVT 227
                                                  ||.:.:..|..|.||.|.|.|.|..::
Zfish   405 --------------------------------------YCRKDYFDMFAPKCGGCARAILENYIS 431

  Fly   228 ALGKHWHVEHFVCAKCEKPFLGHRHYEKRGLAYCETHYHQLFGNLCFVCNQVIGGDVFTALNKAW 292
            ||...||.|.|||.:|..||:....:|..|..|||.|||:..|:||..|.:.|.|...||:.|.:
Zfish   432 ALNSLWHPECFVCRECFTPFVNGSFFEHEGQPYCEAHYHERRGSLCSGCQKPITGRCITAMGKKF 496

  Fly   293 CVHHFACSVCDTKMTQKSKFYEYDEKPVCKKCY 325
            ...||.|:.| .|...|..|.|.::||.|:.|:
Zfish   497 HPEHFVCAFC-LKQLNKGTFKEQNDKPYCQSCF 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stck	NP_731242.1	LIM1_PINCH	21..79	CDD:188717	18/45 (40%)
		LIM2_PINCH	82..133	CDD:188718	13/50 (26%)
		LIM3_PINCH	146..206	CDD:188719	2/59 (3%)
		LIM4_PINCH	212..265	CDD:188720	23/52 (44%)
		LIM5_PINCH	273..326	CDD:188721	19/53 (36%)
pxna	NP_963882.1	Paxillin	54..229	CDD:281527
		LIM1_Paxillin_like	300..352	CDD:259830	16/41 (39%)
		LIM2_Paxillin	359..410	CDD:188791	15/123 (12%)
		LIM3_Paxillin	418..470	CDD:188793	23/51 (45%)
		LIM4_Paxillin	477..528	CDD:188795	18/51 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920