DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stck and prickle1a

DIOPT Version :9

Sequence 1:	NP_731242.1	Gene:	stck / 40999	FlyBaseID:	FBgn0020249	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	NP_899185.2	Gene:	prickle1a / 368249	ZFINID:	ZDB-GENE-030724-5	Length:	793	Species:	Danio rerio

Alignment Length:	193	Identity:	55/193 - (28%)
Similarity:	81/193 - (41%)	Gaps:	28/193 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 CNKCGEFVIGR-----VIKAMSAS--WHPQCFRCQLCAKELADCGFIKNQNRALCHECNAKVKAE 139
            |..|||.:.|.     |.:|.:|.  |||.||.|..|::.|.|..:..:..:..|...:|::
Zfish   132 CEHCGERLSGGEMAVCVSRAAAAGQCWHPACFTCSTCSELLVDLIYFYHDGKVHCGRHHAEL--- 193

  Fly   140 ITGRYVCQKCHGLI-DEEPLRFRGEVYHGYHFSCTACGTELDSTAREVK-SRPGLAANDMNELYC 202
            :..|  |..|..:| .:|.....|..:|..||||:.|...|......:| .||          :|
Zfish   194 LKPR--CSSCDEIIFADECTEAEGRHWHMKHFSCSECEVILGGQRYIMKDGRP----------FC 246

  Fly   203 LRCHDKMGIPICGACRRPI--EERVVTALGKHWHVEH--FVCAKCEKPFLGHRHYEKRGLAYC 261
            ..|...:....|.||.:.|  :...:|..|.|||...  |.||:|:...||.....::|..||
Zfish   247 CGCFQSLYAEYCQACAQHIGVDHAQMTYDGLHWHATDACFSCAQCKSSLLGCPFLPRQGRIYC 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stck	NP_731242.1	LIM1_PINCH	21..79	CDD:188717
		LIM2_PINCH	82..133	CDD:188718	18/57 (32%)
		LIM3_PINCH	146..206	CDD:188719	16/61 (26%)
		LIM4_PINCH	212..265	CDD:188720	18/54 (33%)
		LIM5_PINCH	273..326	CDD:188721
prickle1a	NP_899185.2	PET_Prickle	28..124	CDD:193602
		LIM1_Prickle	132..191	CDD:188799	18/58 (31%)
		LIM2_Prickle	196..251	CDD:188802	18/66 (27%)
		LIM3_Prickle	256..314	CDD:188804	18/54 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810