DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stck and Prickle4

DIOPT Version :9

Sequence 1:	NP_731242.1	Gene:	stck / 40999	FlyBaseID:	FBgn0020249	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	XP_038940411.1	Gene:	Prickle4 / 316212	RGDID:	1563979	Length:	368	Species:	Rattus norvegicus

Alignment Length:	241	Identity:	50/241 - (20%)
Similarity:	65/241 - (26%)	Gaps:	114/241 - (47%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 HTQCFVCAQCFRPFQDGIFYEFEGRKYCERDFHVLFAPCCNKCGEFVIGRVIKAMSASWHPQCFR 107
            || |..|.:...|.:.|:|....|.:            ||                  ||..||.
  Rat   122 HT-CEKCKKLLNPGEYGVFAARAGER------------CC------------------WHRPCFA 155

  Fly   108 CQLCAKELADCGFIKNQNRALCHECNAKVKAEITGRYVCQKCHGLIDEEPLRFRGEVYHGYHFSC 172
            ||.|.:.|.:..:.                                           ||..|
  Rat   156 CQACGQALTNLIYF-------------------------------------------YHDGH--- 174

  Fly   173 TACGTELDSTAREVKSRPGLAANDMNELYCLRCHDKMGIPICGACRRPI-EERVVTALGKHWHVE 236
                                       |||.|.|.::..|.|.||.:.| .:|...|.|:|||..
  Rat   175 ---------------------------LYCGRHHAELLRPRCPACDQLIFSQRCTEAEGRHWHEN 212

  Fly   237 HFVCAKCEKPFLGHRHYEKRGLAYCETHYHQLFGNLCFVCNQVIGG 282
            ||.|..|.:|..|.|:....|...|.:         ||......||
  Rat   213 HFCCQDCAEPLDGGRYALPGGSPCCPS---------CFARRYRSGG 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stck	NP_731242.1	LIM1_PINCH	21..79	CDD:188717	8/35 (23%)
		LIM2_PINCH	82..133	CDD:188718	9/50 (18%)
		LIM3_PINCH	146..206	CDD:188719	7/59 (12%)
		LIM4_PINCH	212..265	CDD:188720	20/53 (38%)
		LIM5_PINCH	273..326	CDD:188721	4/10 (40%)
Prickle4	XP_038940411.1	PET_OEBT	1..116	CDD:193603
		LIM1_Testin_like	124..181	CDD:188726	23/159 (14%)
		LIM2_Testin_like	187..241	CDD:188727	20/62 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910