DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stck and Prickle2

DIOPT Version :9

Sequence 1:	NP_731242.1	Gene:	stck / 40999	FlyBaseID:	FBgn0020249	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	XP_038963548.1	Gene:	Prickle2 / 312563	RGDID:	1306723	Length:	939	Species:	Rattus norvegicus

Alignment Length:	282	Identity:	72/282 - (25%)
Similarity:	101/282 - (35%)	Gaps:	82/282 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 PTEKI--VNSNGE------LWHTQCFVCAQCFRPFQDGIFYEFEGRKYCE--------------- 71
            |.||:  |||.||      |.|.        ..|..:.:       :||.
  Rat   149 PEEKVPYVNSPGEKLRIKQLLHQ--------LPPHDNEV-------RYCNSLDEEEKRELKLFSN 198

  Fly    72 ------------RDFHV-LFAPCCNKCGEFVIGRVIKAMSAS-------WHPQCFRCQLCAKELA 116
                        |.|.| :....|.:||..:.|..| |:.||       |||.||.|.:|.:.|.
  Rat   199 QRKRENLGRGNVRPFPVTMTGAICEQCGGQIKGGDI-AVFASRAGHGICWHPPCFICTVCNELLV 262

  Fly   117 DCGFIKNQNRALCHECNAK-VKAEITGRYVCQKCHGLI-DEEPLRFRGEVYHGYHFSCTACGTEL 179
            |..:.....:..|...:|: :|..      |..|..:| .:|.....|..:|..||.|..|.|.|
  Rat   263 DLIYFYQDGKIYCGRHHAECLKPR------CAACDEIIFADECTEAEGRHWHMRHFCCFECETVL 321

  Fly   180 DSTAREVK-SRPGLAANDMNELYCLRCHDKMGIPICGACRR--PIEERVVTALGKHWHVEH--FV 239
            ......:| .||          ||..|.:.:....|..|.:  .|::..:|..|:|||...  |.
  Rat   322 GGQRYIMKEGRP----------YCCHCFESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATENCFC 376

  Fly   240 CAKCEKPFLGHRHYEKRGLAYC 261
            ||.|:|..||.....|:|..:|
  Rat   377 CAHCKKSLLGRPFLPKQGQIFC 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stck	NP_731242.1	LIM1_PINCH	21..79	CDD:188717	16/84 (19%)
		LIM2_PINCH	82..133	CDD:188718	18/57 (32%)
		LIM3_PINCH	146..206	CDD:188719	17/61 (28%)
		LIM4_PINCH	212..265	CDD:188720	18/54 (33%)
		LIM5_PINCH	273..326	CDD:188721
Prickle2	XP_038963548.1	PET_Prickle	118..214	CDD:193602	14/79 (18%)
		LIM1_Prickle	222..280	CDD:188799	18/58 (31%)
		LIM2_Prickle	285..340	CDD:188802	18/70 (26%)
		LIM3_Prickle	345..403	CDD:188804	18/54 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810