DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stck and Lmcd1

DIOPT Version :9

Sequence 1:	NP_731242.1	Gene:	stck / 40999	FlyBaseID:	FBgn0020249	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	NP_659048.1	Gene:	Lmcd1 / 30937	MGIID:	1353635	Length:	365	Species:	Mus musculus

Alignment Length:	404	Identity:	82/404 - (20%)
Similarity:	134/404 - (33%)	Gaps:	130/404 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 AEVVQAAN-----MSLG------AMHCTRC---ADGFEPTEKIVNSNGELWHTQCFVCAQCFRPF 56
            |:|.:..|     ||||      .:.|.||   ..||||            |:...:|..|
Mouse     2 AKVAKDLNPGVQKMSLGQQQSARGVACLRCKGMCSGFEP------------HSWRKICKSC---- 50

  Fly    57 QDGIFYEFEGRKYCERDFHVLFAPCCNKCGEFVIGRVIKAMSASWHPQCFRCQLCAKELADCGF- 120
                        .|.::.|.|.:...:   :..|||::  |.:.:      ..|.|:.....|.
Mouse    51 ------------KCSQEEHCLSSDLDD---DRKIGRLL--MDSKY------ATLTARVKGGDGIR 92

  Fly   121 IKNQNRALC--------------------------------HECNAKVKAEITGRYVC-----QK 148
            |..:||.:.                                .|...|.:..:||....     |.
Mouse    93 IYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKERQPVTGTEGALYRRRQL 157

  Fly   149 CHGL--IDEEPLRFRGEVYHGY--------HFSCTACGT---------ELDSTAREVKSRPGLAA 194
            .|.|  .|::|.|.||.|.:..        |:...|.|.         .|.....:.:.:|
Mouse   158 MHQLPIYDQDPSRCRGLVENELKAMEEFVKHYKSEALGVGEVALPGQGGLPKEENKTQEKP---- 218

  Fly   195 NDMNELYCLRCHDKMGIP------ICGACR--RPIEERVVTA----LGKHWHVEHFVCAKCEKPF 247
             :..|......:..:|.|      :|..|:  .|::..||.|    ..|.||...|.|.||.:|.
Mouse   219 -EGTETTAPTTNGSLGDPSKEVEYVCELCKGAAPVDSPVVYADRAGYSKQWHPTCFQCIKCSEPL 282

  Fly   248 LGHRHYEKRGLAYCETHYHQLFGNLCFVCNQVIGGDVFTAL-NKAWCVHHFACSVCDTKMTQKSK 311
            :...::.|.|..:|..||.:.....|..|:::|..:.:..: :.||...||.|..|:..::.::.
Mouse   283 VDLIYFWKDGAPWCGRHYCESVRPRCSGCDEIIFSEDYQRVEDLAWHRKHFICEGCEQLLSGRAY 347

  Fly   312 FYEYDEK--PVCKK 323
            .....:.  |.|.|
Mouse   348 IVTKGQLLCPTCSK 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stck	NP_731242.1	LIM1_PINCH	21..79	CDD:188717	13/60 (22%)
		LIM2_PINCH	82..133	CDD:188718	11/83 (13%)
		LIM3_PINCH	146..206	CDD:188719	15/83 (18%)
		LIM4_PINCH	212..265	CDD:188720	18/64 (28%)
		LIM5_PINCH	273..326	CDD:188721	12/54 (22%)
Lmcd1	NP_659048.1	PET_testin	116..203	CDD:193604	16/86 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	200..231		3/35 (9%)
		LIM1_Testin_like	243..300	CDD:188726	17/56 (30%)
		LIM	306..359	CDD:295319	10/52 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810