DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stck and PRICKLE4

DIOPT Version :9

Sequence 1:	NP_731242.1	Gene:	stck / 40999	FlyBaseID:	FBgn0020249	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	NP_037529.3	Gene:	PRICKLE4 / 29964	HGNCID:	16805	Length:	384	Species:	Homo sapiens

Alignment Length:	117	Identity:	34/117 - (29%)
Similarity:	48/117 - (41%)	Gaps:	5/117 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 CTRCADGFEPTEKIVNS--NGE--LWHTQCFVCAQCFRPFQDGIFYEFEGRKYCERDFHVLFAPC 81
            |.:|.:..:|.|..|.:  .||  .||..||.|..|.:...:.|::..:|:.||.|....|..|.
Human   124 CEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQACGQALINLIYFYHDGQLYCGRHHAELLRPR 188

  Fly    82 CNKCGEFVIG-RVIKAMSASWHPQCFRCQLCAKELADCGFIKNQNRALCHEC 132
            |..|.:.:.. |..:|....||...|.||.||..|....:........|..|
Human   189 CPACDQLIFSWRCTEAEGQRWHENHFCCQDCAGPLGGGRYALPGGSPCCPSC 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stck	NP_731242.1	LIM1_PINCH	21..79	CDD:188717	19/61 (31%)
		LIM2_PINCH	82..133	CDD:188718	14/52 (27%)
		LIM3_PINCH	146..206	CDD:188719
		LIM4_PINCH	212..265	CDD:188720
		LIM5_PINCH	273..326	CDD:188721
PRICKLE4	NP_037529.3	PET_OEBT	1..116	CDD:193603
		LIM1_Testin_like	124..181	CDD:188726	18/56 (32%)
		LIM2_Testin_like	187..242	CDD:188727	15/54 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810