DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stck and pxl1

DIOPT Version :9

Sequence 1:	NP_731242.1	Gene:	stck / 40999	FlyBaseID:	FBgn0020249	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	NP_596112.1	Gene:	pxl1 / 2540856	PomBaseID:	SPBC4F6.12	Length:	438	Species:	Schizosaccharomyces pombe

Alignment Length:	173	Identity:	44/173 - (25%)
Similarity:	70/173 - (40%)	Gaps:	15/173 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 CNKC-GEFVIGRVIKAMSASWHPQCFRCQLCAKELADCGFIKNQNRALCHECNAKVKAEITGRYV 145
            |:.| |....||:|.|.....|||||:|..|::.|...||...:.:..||   .....:.:.|
pombe   258 CHSCGGSLRAGRIISASGKKLHPQCFKCDTCSQNLEHVGFYYREGKFYCH---LDYHEQFSPR-- 317

  Fly   146 CQKCHGLIDEEPLRFRGEVYHGYHFSCTACGTELDSTAREVKSRPGLAANDMNELYCLRCHDKMG 210
            |:.|...|:::.:....:.:|..|..|..|....:...      |.:..:|:  .:|..|:|...
pombe   318 CKHCKTPIEDQAVHINNDWFHENHHFCAGCSEVFNVNI------PCIYRDDL--YWCQTCYDNKY 374

  Fly   211 IPICGACRRPIEERVVTALGKHWHVEHFVCAKCEKPFLGHRHY 253
            ...|..||:||....|......:|.:.:.|..| ...||...|
pombe   375 AVKCKKCRKPILGISVKGSDGEYHSQCWTCGAC-NALLGDEGY 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stck	NP_731242.1	LIM1_PINCH	21..79	CDD:188717
		LIM2_PINCH	82..133	CDD:188718	19/51 (37%)
		LIM3_PINCH	146..206	CDD:188719	10/59 (17%)
		LIM4_PINCH	212..265	CDD:188720	12/42 (29%)
		LIM5_PINCH	273..326	CDD:188721
pxl1	NP_596112.1	LIM	258..314	CDD:278823	19/58 (33%)
		LIM	318..370	CDD:259829	10/59 (17%)
		LIM	378..428	CDD:259829	12/40 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	50	1.000	Domainoid score	I3371
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
TreeFam	1	0.960	-	-
	5	4.870