Protein Alignment stck and FHL3

DIOPT Version :10

• Sequence 1: NP_731242.1
• Gene: stck / 40999
• FlyBaseID: FBgn0020249
• Length: 348
• Species: Drosophila melanogaster
• Sequence 2: NP_004459.2
• Gene: FHL3 / 2275
• HGNCID: 3704
• Length: 280
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 77/304 - (25%)
• Similarity: 123/304 - (40%)
• Gaps: 43/304 - (14%)

  Fly    44 TQCFVCAQCFRPFQDGIFYEFEGRKYCERDFHVLFAPC-----CNKCGEF--VIG---RVIKAMS 98
            ::.|.||:|    .:.::    ||||.:.|......||     .|.|.|.  :||   |.:....
Human     2 SESFDCAKC----NESLY----GRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYED 58

  Fly    99 ASWHPQCFRCQLCAKELADCGFIKNQNRALCHECNAKVKAEITGRYVCQKCHGLI--DEEPLRFR 161
            ..:|..||||..|.:.|||..|....:..||::|.....:.     .|..|...:  ....|.:.
Human    59 RHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSS-----QCSACGETVMPGSRKLEYG 118

  Fly   162 GEVYHGYHFSCTACGTELDSTAREVKSRPGLAANDMNELYCLRCHDKMGIPICGACRRPIEERVV 226
            |:.:|.:.|.|:.|...|.|.:         ...|....||:.|::....|.|..|.:.:.:..|
Human   119 GQTWHEHCFLCSGCEQPLGSRS---------FVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGV 174

  Fly   227 TALGKHWHVEHFVCAKCEKPFLGHRHYEKRGLAYCETHYHQLFGNLCFVCNQVI----GGDVFTA 287
            |...:.||.|..||..|:.|..|.:...:....||...:.:||...|..|.:.|    ||...:.
Human   175 TYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSF 239

  Fly   288 LNKAWCVHH--FACSVCDTKMTQKSKFYEYDEKPVCKKCYDRFP 329
            .::.|  ||  |:|:.|.|.:..:. |....::.:|:.|....|
Human   240 EDRHW--HHNCFSCARCSTSLVGQG-FVPDGDQVLCQGCSQAGP 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stck	NP_731242.1	LIM1_PINCH	21..79	CDD:188717	9/34 (26%)
		LIM2_PINCH	82..133	CDD:188718	18/55 (33%)
		LIM3_PINCH	146..206	CDD:188719	13/61 (21%)
		LIM4_PINCH	212..265	CDD:188720	15/52 (29%)
		LIM5_PINCH	273..326	CDD:188721	15/58 (26%)
FHL3	NP_004459.2	LIM	<5..33	CDD:413332	11/35 (31%)
		LIM1_FHL3	36..94	CDD:188807	19/57 (33%)
		LIM2_FHL3	98..155	CDD:188811	14/70 (20%)
		LIM3_FHL	162..213	CDD:188732	14/50 (28%)
		LIM4_FHL3	221..276	CDD:188818	14/57 (25%)