Protein Alignment stck and FHL1

DIOPT Version :10

• Sequence 1: NP_731242.1
• Gene: stck / 40999
• FlyBaseID: FBgn0020249
• Length: 348
• Species: Drosophila melanogaster
• Sequence 2: NP_001427698.1
• Gene: FHL1 / 2273
• HGNCID: 3702
• Length: 339
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 67/255 - (26%)
• Similarity: 97/255 - (38%)
• Gaps: 48/255 - (18%)

  Fly    47 FVCAQCFRPFQDGIFYEFEGRKYCERDFHVLFAPCCNKC-GEFVIGRVI---KAMSAS------- 100
            |.|..|..|.|        |:||.::|.|    .||.|| .:|.....:   |.:.|.
Human    21 FDCHYCRDPLQ--------GKKYVQKDGH----HCCLKCFDKFCANTCVECRKPIGADSKEVHYK 73

  Fly   101 ---WHPQCFRCQLCAKELADCGFIKNQNRALCHECNAKVKAEITGRYVCQKCHG-----LIDEEP 157
               ||..||||..|...||:..|:...|:.||::|        |.|....||.|     :..::.
Human    74 NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKC--------TTREDSPKCKGCFKAIVAGDQN 130

  Fly   158 LRFRGEVYHGYHFSCTACGTELDSTAREVKSRPGLAANDMNELYCLRCHDKMGIPICGACRRPIE 222
            :.::|.|:|...|:|:.|...:.:.:...|.         .:.||:.||:......|..|.:.|.
Human   131 VEYKGTVWHKDCFTCSNCKQVIGTGSFFPKG---------EDFYCVTCHETKFAKHCVKCNKAIT 186

  Fly   223 ERVVTALGKHWHVEHFVCAKCEKPFLGHRHYEKRGLAYCETHYHQLFGNLCFVCNQVIGG 282
            ...:|...:.||.:.|||..|.|...|.|........||...|.......|..|...|.|
Human   187 SGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stck	NP_731242.1	LIM1_PINCH	21..79	CDD:188717	10/31 (32%)
		LIM2_PINCH	82..133	CDD:188718	19/64 (30%)
		LIM3_PINCH	146..206	CDD:188719	12/64 (19%)
		LIM4_PINCH	212..265	CDD:188720	15/52 (29%)
		LIM5_PINCH	273..326	CDD:188721	4/10 (40%)
FHL1	NP_001427698.1	None