DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stck and Tgfb1i1

DIOPT Version :9

Sequence 1:	NP_731242.1	Gene:	stck / 40999	FlyBaseID:	FBgn0020249	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	XP_036008777.1	Gene:	Tgfb1i1 / 21804	MGIID:	102784	Length:	496	Species:	Mus musculus

Alignment Length:	252	Identity:	75/252 - (29%)
Similarity:	113/252 - (44%)	Gaps:	31/252 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 CNKCGEFVIGRVIKAMSASWHPQCFRCQLCAKELADCGFIKNQNRALCHECNAKVKAEITGRYV- 145
            |..|.:.:.|:|:.|:..:|||:.|.|..|:..|....|.:......|.||..:       |:.
Mouse   263 CGSCNKPIAGQVVTALGRAWHPEHFLCSGCSTTLGGSSFFEKDGAPFCPECYFE-------RFSP 320

  Fly   146 -CQKCHGLIDEEPLRFR-----GEVYHGYHFSCTACGTEL-DSTAREVKSRPGLAANDMNELYCL 203
             |..|:     :|:|.:     |..:|..||.|.:||... :....|.:.||          ||.
Mouse   321 RCGFCN-----QPIRHKMVTALGTHWHPEHFCCVSCGEPFGEEGFHEREGRP----------YCR 370

  Fly   204 RCHDKMGIPICGACRRPIEERVVTALGKHWHVEHFVCAKCEKPFLGHRHYEKRGLAYCETHYHQL 268
            |...::..|.|..|:.||.:..::||...||.:.|||.:|..||.|...:|..|...||.|:|..
Mouse   371 RDFLQLFAPRCQGCQGPILDNYISALSALWHPDCFVCRECLAPFSGGSFFEHEGRPLCENHFHAQ 435

  Fly   269 FGNLCFVCNQVIGGDVFTALNKAWCVHHFACSVCDTKMTQKSKFYEYDEKPVCKKCY 325
            .|:||..|...:.|...:||.:.:...||.|:.|...:| |..|.|...||.|:.|:
Mouse   436 RGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLT-KGSFQERASKPYCQPCF 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stck	NP_731242.1	LIM1_PINCH	21..79	CDD:188717
		LIM2_PINCH	82..133	CDD:188718	15/50 (30%)
		LIM3_PINCH	146..206	CDD:188719	17/65 (26%)
		LIM4_PINCH	212..265	CDD:188720	20/52 (38%)
		LIM5_PINCH	273..326	CDD:188721	17/53 (32%)
Tgfb1i1	XP_036008777.1	Paxillin	4..>128	CDD:397550
		LIM1_Paxillin_like	263..315	CDD:259830	16/51 (31%)
		LIM2_Paxillin_like	322..373	CDD:188723	17/65 (26%)
		LIM	381..433	CDD:413332	20/51 (39%)
		LIM4_Leupaxin	440..491	CDD:188796	16/51 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920