DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment stck and DMTN

DIOPT Version :9

Sequence 1:	NP_731242.1	Gene:	stck / 40999	FlyBaseID:	FBgn0020249	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	NP_001107607.1	Gene:	DMTN / 2039	HGNCID:	3382	Length:	405	Species:	Homo sapiens

Alignment Length:	108	Identity:	24/108 - (22%)
Similarity:	34/108 - (31%)	Gaps:	40/108 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   147 QKCHGLIDEEPLRFRGEVYHGYHFSCTACGTELDSTAREVKSR---------------PGLAAND 196
            :|...|.|..|  |...::.|     |:..:.|.:..|...||               |||...:
Human   265 RKTRSLPDRTP--FHTSLHQG-----TSKSSSLPAYGRTTLSRLQSTEFSPSGSETGSPGLQNGE 322

  Fly   197 --------MNELYCLRCHDKMGIPICGACRRPIEERVVTALGK 231
                    .|.|.|: ...|:         .|.|..|||..|:
Human   323 GQRGRMDRGNSLPCV-LEQKI---------YPYEMLVVTNKGR 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stck	NP_731242.1	LIM1_PINCH	21..79	CDD:188717
		LIM2_PINCH	82..133	CDD:188718
		LIM3_PINCH	146..206	CDD:188719	17/81 (21%)
		LIM4_PINCH	212..265	CDD:188720	6/20 (30%)
		LIM5_PINCH	273..326	CDD:188721
DMTN	NP_001107607.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..30
		AbLIM_anchor	8..369	CDD:406566	24/108 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	79..158
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	173..192
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	203..332		14/73 (19%)
		Interaction with RASGRF2. /evidence=ECO:0000269\|PubMed:11856323	224..308		11/49 (22%)
		VHP	370..405	CDD:128458
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910