DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stck and alp-1

DIOPT Version :9

Sequence 1:	NP_731242.1	Gene:	stck / 40999	FlyBaseID:	FBgn0020249	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	NP_001023371.1	Gene:	alp-1 / 177701	WormBaseID:	WBGene00001132	Length:	1424	Species:	Caenorhabditis elegans

Alignment Length:	251	Identity:	62/251 - (24%)
Similarity:	83/251 - (33%)	Gaps:	79/251 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 AMHCTRCADGFEPTEKIVNSNGELWHTQCFVCA--QCFRPFQDGIFYEFEGRKYCERDFHVLFAP 80
            |..|..|.......  .|.:.|:.|..:.||||  .|.|...:..|.|.:|:|:||..|....||
Worm  1248 APFCESCKQQIRGA--FVLATGKSWCPEHFVCANSSCRRRLLECGFVEEDGQKFCESCFEQHIAP 1310

  Fly    81 CCNKCGEFVIGRVIKAMSASWHPQCFRCQLCAKELADCGFIKNQNRALCHECNAKVKAEITGRYV 145
            .||||.:.:|...:.|:...|||.||.|..|.|...:..|...|....|.:
Worm  1311 RCNKCSKPIISDCLNALQKKWHPTCFTCAHCQKPFGNSAFYLEQGLPYCEQ-------------- 1361

  Fly   146 CQKCHGLIDEEPLRFRGEVYHGYHFSCTACGTELDSTAREVKSRPGLAANDMNELYCLRCHDKMG 210
                                                              |.|.|:..:
Worm  1362 --------------------------------------------------DWNALFTTK------ 1370

  Fly   211 IPICGACRRPIE--ERVVTALGKHWHVEHFVCAKCEKPFLGHRHYEKRGLAYCETH 264
               |.:||.|||  :|.|.|||..:|...|.||:|.....|...:.|.|..:|..|
Worm  1371 ---CVSCRYPIEAGDRWVEALGNAFHSNCFTCARCNHNLEGESFFAKNGQPFCRLH 1423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stck	NP_731242.1	LIM1_PINCH	21..79	CDD:188717	18/59 (31%)
		LIM2_PINCH	82..133	CDD:188718	17/50 (34%)
		LIM3_PINCH	146..206	CDD:188719	3/59 (5%)
		LIM4_PINCH	212..265	CDD:188720	21/55 (38%)
		LIM5_PINCH	273..326	CDD:188721
alp-1	NP_001023371.1	PDZ_signaling	5..80	CDD:238492
		DUF4749	137..>197	CDD:292558
		ZM	137..162	CDD:128974
		LIM_ALP_like	220..271	CDD:188746
		LIM1_Enigma_like_1	1251..1304	CDD:188839	17/54 (31%)
		LIM	1312..1363	CDD:295319	17/114 (15%)
		LIM3_Enigma_like_1	1371..1424	CDD:188845	21/53 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1593918at2759
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920