DRSC/TRiP Functional Genomics Resources

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Protein Alignment stck and Lpxn

DIOPT Version :9

Sequence 1:NP_731242.1 Gene:stck / 40999 FlyBaseID:FBgn0020249 Length:348 Species:Drosophila melanogaster
Sequence 2:NP_598913.1 Gene:Lpxn / 107321 MGIID:2147677 Length:386 Species:Mus musculus


Alignment Length:307 Identity:85/307 - (27%)
Similarity:122/307 - (39%) Gaps:79/307 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 CADGFEP-TEKIVNSNGELWHTQCFVCAQCFRPFQDGIFYEFEGRKYCERDFHVLFAPCCNKCGE 87
            ||...:| ..|::::.|:.||.:.|||..|........|:|..|..||.:|:|.||:|.|..|..
Mouse   152 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEELGSSPFFERSGLAYCSKDYH
RLFSPRCAYCAA 216

  Fly    88 FVIGRVIKAMSASWHPQCFRCQLCAKELADCGFIKNQNRALCHECNAKVKAEITGRYVCQKCHGL 152
            .:..:|:.||:.:|||:.|.|..|                                         
Mouse   217 PITDKVLTAMNKTWHPEHFFCSHC----------------------------------------- 240

  Fly   153 IDEEPLRFRGEVY--HGYHFSCTACGTELDSTAREVKSRPGLAANDMNELYCLRCHDKMGIPICG 215
                     |||:  .|:|               |...:|          ||.:....|..|.||
Mouse   241 ---------GEVFGAEGFH---------------EKDKKP----------YCRKDF
LAMFSPKCG 271

  Fly   216 ACRRPIEERVVTALGKHWHVEHFVCAKCEKPFLGHRHYEKRGLAYCETHYHQLFGNLCFVCNQVI 280
            .|.||:.|..::|:...||.|.|||..|...|.....:|..|..:||.|||...|.||..|.|.|
Mouse   272 GCNRPVLENYLSAMNTVWHPECFVCGDCFSSFSSGSFFELDGRPFCELHYH
HRRGTLCHDCGQPI 336

  Fly   281 GGDVFTALNKAWCVHHFACSVCDTKMTQKSKFYEYDEKPVCKKCYDR 327
            .|...:|:...:...||.|:.|.|:: .|..|.|.:.|..|:||:.:
Mouse   337 TGRCISAMGHKFHPEHFVCAFCLTQL-PKGIFKEQNNKTYCEKCFTK 382

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
stckNP_731242.1 LIM1_PINCH 21..79 CDD:188717 19/55 (35%)
LIM2_PINCH 82..133 CDD:188718 11/50 (22%)
LIM3_PINCH 146..206 CDD:188719 9/61 (15%)
LIM4_PINCH 212..265 CDD:188720 20/52 (38%)
LIM5_PINCH 273..326 CDD:188721 18/52 (35%)
LpxnNP_598913.1 LD motif 1 3..15
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 19..52
LD motif 2 70..82
LD motif 3 92..103
LIM 150..204 CDD:295319 17/51 (33%)
LIM 211..262 CDD:295319 20/125 (16%)
LIM 270..322 CDD:295319 20/51 (39%)
LIM4_Paxillin_like 329..380 CDD:188725 17/51 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1593918at2759
OrthoFinder 1 1.000 - - FOG0000055
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X39
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.920

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