DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stck and fhl5

DIOPT Version :9

Sequence 1:	NP_731242.1	Gene:	stck / 40999	FlyBaseID:	FBgn0020249	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	NP_001116957.1	Gene:	fhl5 / 100144736	XenbaseID:	XB-GENE-1002465	Length:	282	Species:	Xenopus tropicalis

Alignment Length:	296	Identity:	72/296 - (24%)
Similarity:	122/296 - (41%)	Gaps:	44/296 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 CFVCAQCFRPFQDGIFYEFEGRK--------YCERDFHVLFAPCCNKCGEFV--IGRVIKAMSAS 100
            ||.|.:           ...|:|        ||.:.|:.|||..|.:|.:.:  ..:.:....:.
Frog     8 CFHCKE-----------SLYGKKYTLKDDIPYCIKCFNSLFANLCERCKKPIECNSKDLAYKDSH 61

  Fly   101 WHPQCFRCQLCAKELADCGFIKNQNRALCHECNAKVKAEITGRYVCQKCHGLI--DEEPLRFRGE 163
            ||..||:|..|...|.:..|.......||.||   ...|.:.:  |..|...|  ....:.:.|.
Frog    62 WHETCFKCDKCDHSLVEKPFAAKDELLLCIEC---YSTEYSSK--CFGCRATIMPGSRKMEYNGS 121

  Fly   164 VYHGYHFSCTACGTELDSTARE-VKSRPGLAANDMNELYCLRCHDKMGIPICGACRRPIEERVVT 227
            .:|...|.|.:|        || |.::|.:...  :::||:.|::|.....|.:||:.|.:..::
Frog   122 NWHETCFVCQSC--------REPVGNKPFIPKE--SKIYCMPCYEKQFANQCKSCRKAITKGGLS 176

  Fly   228 ALGKHWHVEHFVCAKCEKPFLGHRHYEKRGLAYCETHYHQLFGNLCFVCNQVI---GGDVFTAL- 288
            ...:.||.|.|||..|:|..:|.:...:....||...:..|:...|..|.:.|   ||..:.:.
Frog   177 FQEQQWHRECFVCTSCKKNLVGEKSTSRDESPYCVDCFDNLYAKKCAACAKPITGQGGAKYISFE 241

  Fly   289 NKAWCVHHFACSVCDTKMTQKSKFYEYDEKPVCKKC 324
            ::.|....|.|:.| :|.....||:..::..:|..|
Frog   242 DRQWHSDCFTCAKC-SKSLVGEKFHTNEDDVLCPSC 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stck	NP_731242.1	LIM1_PINCH	21..79	CDD:188717	9/40 (23%)
		LIM2_PINCH	82..133	CDD:188718	13/52 (25%)
		LIM3_PINCH	146..206	CDD:188719	14/62 (23%)
		LIM4_PINCH	212..265	CDD:188720	15/52 (29%)
		LIM5_PINCH	273..326	CDD:188721	14/56 (25%)
fhl5	NP_001116957.1	LIM	<6..33	CDD:351770	7/35 (20%)
		LIM1_FHL	37..95	CDD:188729	16/60 (27%)
		LIM2_FHL	102..155	CDD:188731	14/62 (23%)
		LIM3_FHL	163..214	CDD:188732	15/50 (30%)
		LIM4_FHL	222..277	CDD:188733	14/56 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51900
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000055
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920