DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stck and prickle2

DIOPT Version :9

Sequence 1:	NP_731242.1	Gene:	stck / 40999	FlyBaseID:	FBgn0020249	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	XP_031757102.1	Gene:	prickle2 / 100126208	XenbaseID:	XB-GENE-482891	Length:	893	Species:	Xenopus tropicalis

Alignment Length:	276	Identity:	66/276 - (23%)
Similarity:	88/276 - (31%)	Gaps:	91/276 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 GAMHCTRCADGFEPTEKIV----NSNGELWHTQCFVCAQCFRPFQDGIFYEFEGRKYCERDFHVL 77
            ||: |.:|.......:..|    ..:|..||.|||||..|.....|.|::..:|:.||.|.....
Frog   183 GAI-CEQCGGQINGGDMAVFASRAGHGVCWHPQCFVCIICNELLVDLIYFYQDGKIYCGRHHAEC 246

  Fly    78 FAPCCNKCGEFVIGRVIKAMSASWHPQCFRCQLCAKELADCGFIKNQNRALCHECNAKVKAEITG 142
            ..|.|..|.|.:                         .||             ||     .|..|
Frog   247 LKPRCAACDEII-------------------------FAD-------------EC-----TEAEG 268

  Fly   143 RYVCQKCHGLIDEEPLRFRGEVYHGYHFSCTACGTELDSTAREVK-SRPGLAANDMNELYCLRCH 206
            |:                    :|..||.|..|.|.|......:| .||          ||..|.
Frog   269 RH--------------------WHMKHFCCFECETVLGGQRYIMKEGRP----------YCCNCF 303

  Fly   207 DKMGIPICGACRR--PIEERVVTALGKHWHVEH--FVCAKCEKPFLGHRHYEKRGLAYCETHYHQ 267
            :.:....|..|.:  .|::..:|..|:|||...  |.||.|:|..||.....|:|..:|
Frog   304 ESLYAEYCDTCAQHIGIDQGQMTYDGQHWHATENCFCCAHCKKSLLGRPFLPKQGQIFC------ 362

  Fly   268 LFGNLCFVCNQVIGGD 283
              ...|.|.....|.|
Frog   363 --SRACSVGEDPNGSD 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stck	NP_731242.1	LIM1_PINCH	21..79	CDD:188717	18/61 (30%)
		LIM2_PINCH	82..133	CDD:188718	6/50 (12%)
		LIM3_PINCH	146..206	CDD:188719	12/60 (20%)
		LIM4_PINCH	212..265	CDD:188720	18/56 (32%)
		LIM5_PINCH	273..326	CDD:188721	4/11 (36%)
prickle2	XP_031757102.1	PET_Prickle	82..178	CDD:193602
		LIM1_Prickle	186..244	CDD:188799	18/57 (32%)
		LIM2_Prickle	249..304	CDD:188802	24/127 (19%)
		LIM3_Prickle	309..367	CDD:188804	18/65 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X39
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000