Protein Alignment Atg13 and ATG13

DIOPT Version :10

• Sequence 1: NP_649796.1
• Gene: Atg13 / 40998
• FlyBaseID: FBgn0261108
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_015511.1
• Gene: ATG13 / 856315
• SGDID: S000006389
• Length: 738
• Species: Saccharomyces cerevisiae
• Alignment Length: 689
• Identity: 133/689 - (19%)
• Similarity: 235/689 - (34%)
• Gaps: 228/689 - (33%)

  Fly     9 AERDLEKFIKFLV----LKSTQVVVQSRLGEKMQTQCNPLAGSD-WFNIAVQDHPEVLDETKRAL 68
            ||.|:||.:..|:    ||:|.::..:.......:..|.....| ||    :||.|::.|....:
Yeast     3 AEEDIEKQVLQLIDSFFLKTTLLICSTESSRYQSSTENIFLFDDTWF----EDHSELVSELPEII 63

  Fly    69 NLKTGESILQRL-PLCVE-------------ISLKTTEG-----------DQMVLEVWSLDLLQP 108
            :..:.....:.| ||.||             :.||..||           .::|:|.|.::|
Yeast    64 SKWSHYDGRKELPPLVVETYLDLRQLNSSHLVRLKDHEGHLWNVCKGTKKQEIVMERWLIEL--- 125

  Fly   109 QNGASPA----TNDLNPEGQTLKAAHAIYNRMGIMLKSLISLTRTTPAYKL-------------- 155
             :.:||.    :.|.....:..|....::.    .|.:||.|..||..|:|
Yeast   126 -DNSSPTFKSYSEDETDVNELSKQLVLLFR----YLLTLIQLLPTTELYQLLIKSYNGPQNEGSS 185

  Fly   156 ----------SRRQC--PDSYGIFY--RIYVDRPQVHT----LGEGH--KHV---KIGQLSTIVG 197
                      |.|.|  ..|..|..  ||.:.:|.::|    |.|.:  .|:   ||..:.|..|
Yeast   186 NPITSTGPLVSIRTCVLDGSKPILSKGRIGLSKPIINTYSNALNESNLPAHLDQKKITPVWTKFG 250

  Fly   198 SLVMSVAYRT--KLTISPTAAQSESNTIMLKSDHFRPATDANTPGNQ--QQTQNGTVVAKKLGLG 258
            .|.:||:||.  |..|:.|      |..:..:.|...:.::..|.||  |:.|:...:.|:
Yeast   251 LLRVSVSYRRDWKFEINNT------NDELFSARHASVSHNSQGPQNQPEQEGQSDQDIGKR---- 305

  Fly   259 ALNP----------------------------AQGTADRRFIDIEKPLRPGAFTDMGKLKQYTED 295
              .|                            .:...|||.:.:....|..:|......|:
Yeast   306 --QPQFQQQQQPQQQQQQQQQQQRQHQVQTQQQRQIPDRRSLSLSPCTRANSFEPQSWQKK---- 364

  Fly   296 DFVLPETPPFEWLLRGRGSVESLNRLDNNS-------VASVNISNNNNSTQDSKFNQISNLNNNS 353
              |.|.:.|.:....|....:|.:|..:||       |...::|:|.....:.:...:.:.:..|
Yeast   365 --VYPISRPVQPFKVGSIGSQSASRNPSNSSFFNQPPVHRPSMSSNYGPQMNIEGTSVGSTSKYS 427

  Fly   354 AGFKSFEK--------NSENSVSPIKSLLIPASATATYRH-----HSEPSL--------QPP--- 394
            :.|.:..:        |:|.....:||.|.|..:......     ..:|.|        .||
Yeast   428 SSFGNIRRHSSVKTTENAEKVSKAVKSPLQPQESQEDLMDFVKLLEEKPDLTIKKTSGNNPPNIN 492

  Fly   395 ------------PDDDNLLKELHFPFASPTSHVNDLAKFYRECYHAPPLKGLNELQAEISSISST 447
                        |.:|.|.::|....:...:|.          ||    :|.::..:.:.|||.:
Yeast   493 ISDSLIRYQNLKPSNDLLSEDLSVSLSMDPNHT----------YH----RGRSDSHSPLPSISPS 543

  Fly   448 ----------PPASSGSGGVAACGPTAAATAIAT------SSADASAMDDLS------------- 483
                      ...::.|..:|..|..::.:|:.:      .|::...|..|.
Yeast   544 MHYGSLNSRMSQGANASHLIARGGGNSSTSALNSRRNSLDKSSNKQGMSGLPPIFGGESTSYHHD 608

  Fly   484 ------RQLEQFETSLEDYDKLVSQFGLTGSSSTGSRSS 516
                  .||...|...::.|:|::|.   |:|:|..:||
Yeast   609 NKIQKYNQLGVEEDDDDENDRLLNQM---GNSATKFKSS 644

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atg13	NP_649796.1	ATG13	22..207	CDD:431003	56/251 (22%)
ATG13	NP_015511.1	ATG13	15..261	CDD:431003	57/257 (22%)