DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Atg13 and ATG13

DIOPT Version :9

Sequence 1:	NP_649796.1	Gene:	Atg13 / 40998	FlyBaseID:	FBgn0261108	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	NP_001190043.1	Gene:	ATG13 / 824121	AraportID:	AT3G49590	Length:	618	Species:	Arabidopsis thaliana

Alignment Length:	588	Identity:	127/588 - (21%)
Similarity:	206/588 - (35%)	Gaps:	149/588 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LEKFIKFLVLKSTQVVVQSRLGEKMQTQ---------CNPLAGSDWFNIAVQDHPEVLDETKRAL 68
            ||:.:.....|:..:|:.||: ..:|::         .|......|||:.:.|.|..| |...:.
plant    14 LEQIVSHFFPKALHIVLNSRI-PSLQSRGRTRERLSGLNVRKSDKWFNLVMGDRPAAL-EKLHSW 76

  Fly    69 NLKTGESILQRLPLCVEISLKTTEGD-----------QMVLEVWSLDLLQPQNG--ASPATNDLN 120
            :....:|::..:.|...||....:.|           :.|:|.|   ::|.:|.  .||.::|..
plant    77 HRNILDSMIIDIILVHPISNDNLDDDDDHSDSVVRSAETVIERW---VVQYENPLIMSPQSSDSA 138

  Fly   121 PEGQTLKAAHAIYNRMGIMLKSLISLTRTTPAYKLSRR----QCPDSYGIFYRI-----YVDRPQ 176
            ...|      .:|.:..|:|:||.:.||..|||::||:    .....|.:.|::     ....|.
plant   139 TRYQ------KVYKKSIILLRSLYAQTRLLPAYRVSRQLSSSLASSGYDLIYKVSSFSDIFSGPV 197

  Fly   177 VHTLGEGHKHVKIGQLSTIVGSLVMSVAYRTKL---------TISPTAAQSESNTIMLKSDHF-R 231
            ..|:    |..:...:....|.|..||.||:.|         |:.|          .:.:|:. .
plant   198 TETM----KEFRFAPVEVPPGRLCASVTYRSDLSDFNLGAHITLPP----------RIITDYVGS 248

  Fly   232 PATDA----NTPGNQQQTQNGTVVAKKLGLGALN--------------PAQ-GTADRRFIDIEK- 276
            ||||.    .:||...:..:.|..|.:..|...:              ||| .|.::.|...:.
plant   249 PATDPMRFFPSPGRSVEGHSFTGRAGRPPLTGSSAERPHSWTSGFHRPPAQFATPNQSFSPAQSH 313

  Fly   277 PLRPG----------AFTDMGKLKQYTEDDFVLPETPPFEWLLRGRGSVESLNRLDNNSVASVNI 331
            .|.||          ||.|..:|            :|||.    ..||..:...:...:...:|:
plant   314 QLSPGLHDFHWSRTDAFGDNHQL------------SPPFS----PSGSPSTPRYISGGNSPRINV 362

  Fly   332 SNNNNSTQDSKFNQISNLNNN-SAGFKSFEKNSENSVSPIKSLLIPAS-----ATATYRHHSEPS 390
               ...|........:.||.. |:.|....:|.....||..:...|:|     ..|.||  |..|
plant   363 ---RPGTAPVTIPSSATLNRYVSSNFSEPGRNPLPPFSPKSTRRSPSSQDSLPGIALYR--SSRS 422

  Fly   391 LQPPPDDDNLLKELHFPFASPTSHVNDLAKF----YRECYHAPPLKGLNELQAEISSISSTPPAS 451
            .:.|   ..|:.:.      ||..|..|..:    .:|.||.............:||..|...|.
plant   423 GESP---SGLMNQY------PTQKVMLLTSYVSCSMQEKYHYIFKYDSGRFSGVLSSSDSPRFAF 478

  Fly   452 SGSGGVAACGPTAAATAIATSSADASA---MDDLSRQLEQFETSLEDYDKLVSQFGLTGSSSTGS 513
            |.|       |:..::.......|.|.   .||:.....|:..||   |:..:...::.|...|.
plant   479 SRS-------PSRLSSQDDLDDPDCSCPFDFDDVDESGLQYSHSL---DRRKTSSSISQSLPLGR 533

  Fly   514 RSS 516
            |||
plant   534 RSS 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atg13	NP_649796.1	ATG13	22..207	CDD:287051	49/215 (23%)
ATG13	NP_001190043.1	ATG13	18..229	CDD:287051	51/225 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004173
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13430
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010