Protein Alignment DppIII and YOL057W

DIOPT Version :10

• Sequence 1: NP_731237.1
• Gene: DppIII / 40996
• FlyBaseID: FBgn0037580
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_014584.1
• Gene: YOL057W / 854097
• SGDID: S000005418
• Length: 711
• Species: Saccharomyces cerevisiae
• Alignment Length: 735
• Identity: 277/735 - (37%)
• Similarity: 410/735 - (55%)
• Gaps: 71/735 - (9%)

  Fly    69 AHFVLPNTQPIADLDCKSA-FENLTEKEKLYAHHFSQASWDGGLIALIQSSPEAPLIFSLLHRIF 132
            :||...:..|::.|..|:. |..||:||:.|||..|:||..|..:.:.|.|.|:..||.|:..|.
Yeast     2 SHFFADHDAPLSMLSVKTEYFPQLTDKEQKYAHFMSKASHAGSRVVMRQVSHESEPIFDLILAIH 66

  Fly   133 --LAEKIPVLRAKALEAGVSADDFT------AFLVYACGVFANAGNYKGMGDSKIVPNLSEKQFE 189
              |..|.|            .||.|      .:|.|.....:|.||:|..||:|.:|....|.|:
Yeast    67 SKLNGKYP------------EDDITQKQQTGLYLEYVSQFLSNLGNFKSFGDTKFIPRCEVKFFK 119

  Fly   190 TIVK-------------ASAAYSDEPRVGKIFEKVKNL----IYALESRNEILGFAPDGITT--Y 235
            .:::             :....:.|.....:|..:..|    ||.:|.:..:|||...|.|:  |
Yeast   120 QLLELAKINPCSSPLTLSPVDVNHEFTSHHLFSTINELIDIGIYHVEEKAALLGFPSQGYTSAYY 184

  Fly   236 WSDNCTKEDSEIVNAWLTSK-RIEPYMCRTFKIVENGQTVYDVKLGSVAESTQDGITLPLEEYNG 299
            .....|.||..::...|.:: .|.|...|..|:.||...::     ..:|:.::.||   |.|..
Yeast   185 LGLPVTPEDMALLKEQLFAELAILPENTRINKVGENSFQIW-----VASENVKNQIT---ETYPS 241

  Fly   300 NKFRVTR---------GDYQKLLQRVNQHLLQAQKYAANENESKMIEHYVRSFEQGSLDEHKNGS 355
            .:..::.         ||:.:.::.|..:|.:|||:|||:.:..|::.|:..|..||...||...
Yeast   242 GQITLSNAVTKVEFIFGDHSREMRLVASYLKEAQKFAANDTQKAMLQEYINHFVTGSSQAHKEAQ 306

  Fly   356 RWWIKDKGPVIETYIGFIETYRDPAGGRAEFEGFVAMVNKESSAKFSELVNRAEKLIEYLPWTEP 420
            :.|:||..|||||.||||||||:|:|...|||..||:.|||.:||||.|||.||:.|..|||::.
Yeast   307 KLWVKDISPVIETNIGFIETYREPSGIIGEFESLVAIQNKERTAKFSSLVNNAEEFISLLPWSKD 371

  Fly   421 YEKDSYLKPDFTSLDVLTFAGSGVPAGINIPNYDEIRQDEGFKNVSLGNVL---ANINRKDPIPF 482
            |||..:..||||||:||||.|||:||||||||||::|...|||||||||:|   |..:.|.|..|
Yeast   372 YEKPIFNPPDFTSLEVLTFTGSGIPAGINIPNYDDVRLKIGFKNVSLGNILSAAAKSSSKHPPSF 436

  Fly   483 LTEEDQTLMKEYKVKAFEVQVGLHELLGHGSGKLFRIDENGVYNFDKENTKNLVTGEPITKWYLP 547
            :::||:.:.::|:..:||||||:|||||||||||.....:| :||||||....:.|:|::.:|..
Yeast   437 ISQEDRPIFEKYQSDSFEVQVGIHELLGHGSGKLLTEFTDG-FNFDKENPPLGLDGKPVSTYYKV 500

  Fly   548 GETYDTKFGAIGSSYEECRAEAVGLYLSLQRDILEIFGFKDKAEQDNIIYVNWLSLIWNGMGVAL 612
            |||:.:|||.:...:||||||.:.::|...:.||:||||.|...||.:||..:|.:...|: :||
Yeast   501 GETWGSKFGQLAGPFEECRAEVIAMFLLTNKKILDIFGFHDVESQDKVIYAGYLQMARAGL-LAL 564

  Fly   613 EMFNPKSKLWLQAHSRARFVIMKVLLE--AGEGLVKVEETEKGKNLLLTVDRSKIDTVGRKALGD 675
            |.:|||:..|.|.|.:|||.|||..::  ..:..:|:|......:..:.:|:|.|.|.|.:.:.|
Yeast   565 EYWNPKTGKWGQPHMQARFSIMKTFMKHSTDKNFLKLEMNSTNDDFAIKLDKSLIKTAGHECVKD 629

  Fly   676 FLTKLQVYKSTADIEAASKMYEHYSKVDESGSHP-WAKWRDICLAHKKPRMILVQANTAIGQDQK 739
            :|..|.|||.:.|:|..||.:     :|.|...| .|..|||.|:.:.||...:|:|:.|..:.|
Yeast   630 YLKHLHVYKCSGDVEQGSKYF-----IDRSTVTPDLASLRDIVLSKRLPRRQFIQSNSYIDDNNK 689

  Fly   740 VQLKTYEPTHEGYIQSWVER 759
            |.||.|:.|.:|.:||:::|
Yeast   690 VTLKEYDETPQGMLQSFLDR 709

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DppIII	NP_731237.1	Peptidase_M49	207..760	CDD:460976	234/575 (41%)
YOL057W	NP_014584.1	Peptidase_M49	154..710	CDD:460976	233/571 (41%)