Protein Alignment DppIII and dpp3

DIOPT Version :10

• Sequence 1: NP_731237.1
• Gene: DppIII / 40996
• FlyBaseID: FBgn0037580
• Length: 786
• Species: Drosophila melanogaster
• Sequence 2: NP_001002683.1
• Gene: dpp3 / 322527
• ZFINID: ZDB-GENE-030131-1247
• Length: 727
• Species: Danio rerio
• Alignment Length: 722
• Identity: 363/722 - (50%)
• Similarity: 500/722 - (69%)
• Gaps: 17/722 - (2%)

  Fly    69 AHFVLPNTQPIADLDCKSAFENLTEKEKLYAHHFSQASWDGGLIALIQSSPEAPLIFSLLHRIFL 133
            :.:.|||...|:.|||:.||:.|:.|||||||:.|:|:|.|||:.|||:|||:..|:.||.::|.
Zfish     4 SQYYLPNDIGISALDCREAFKLLSPKEKLYAHYLSRAAWYGGLVVLIQTSPESAKIYVLLQKMFR 68

  Fly   134 AEKIPVLRAKALEAGVSADDFTAFLVYACGVFANAGNYKGMGDSKIVPNLSEKQFETIVKASAAY 198
            |:....::..|..||:||:::.||||||.|:|||.||||..||:|.:|||.:::|:.:|..|.|:
Zfish    69 AQTPLQMQETATAAGLSAEEYQAFLVYAAGLFANMGNYKSFGDTKFIPNLPKEKFKALVWESLAF 133

  Fly   199 SDEPRVGKI-FEKVKNLIYALESRNEILGFAPDGITTYWSDNCTKEDSEIVNAWLTSKRIEPYMC 262
            .::|...:: :......:|:||.:.:.||....|||.|:|.||..||:|....:|.||.:..|..
Zfish   134 KEDPSGTEVLWNSCCEPLYSLEEKQKQLGLGEKGITAYFSGNCCLEDAEFAQKFLDSKNLSAYNT 198

  Fly   263 RTFKIVENGQTVYDVKLGSV------AESTQDGITLPLEEYNGNKFRVTRGDYQKLLQRVNQHLL 321
            |.||...:|:..|:|:|.|.      ||..:........|:....|.|.||||..|:::|.|:|.
Zfish   199 RLFKTEVDGKRCYEVRLASAKTEDCCAEEGEGKTCCGRFEFEDAVFCVKRGDYSFLMEKVCQNLE 263

  Fly   322 QAQKYAANENESKMIEHYVRSFEQGSLDEHKNGSRWWIKDKGPVIETYIGFIETYRDPAGGRAEF 386
            :|:..||:||:.:|:|.|:|||..||::.||.|||:|||||||::|:||||||:||||.|.|.||
Zfish   264 KAKVNAADENQRRMLEEYIRSFTYGSVEAHKEGSRFWIKDKGPIVESYIGFIESYRDPFGSRGEF 328

  Fly   387 EGFVAMVNKESSAKFSELVNRAEKLIEYLPWTEPYEKDSYLKPDFTSLDVLTFAGSGVPAGINIP 451
            |||||:|||..||:|::||:.||.|:..|||...:|||.:|||||||||||||||||:|||||||
Zfish   329 EGFVAVVNKAMSARFAQLVSSAEVLLPELPWPPAFEKDRFLKPDFTSLDVLTFAGSGIPAGINIP 393

  Fly   452 NYDEIRQDEGFKNVSLGNVL--ANINRKDPIPFLTEEDQTLMKEYKVKAFEVQVGLHELLGHGSG 514
            |||:|||.||||||||||||  |...:||.:.||.|:|:.|..::|..:||||||||||||||||
Zfish   394 NYDDIRQTEGFKNVSLGNVLAVAYATQKDKLTFLEEKDKDLYIKWKGPSFEVQVGLHELLGHGSG 458

  Fly   515 KLFRIDENGVYNFDKENTKNLVTGEPITKWYLPGETYDTKFGAIGSSYEECRAEAVGLYLSLQRD 579
            |||..|:.|.:|||:...:|..|||.|:.||...||:|:||..|.|||||||||.|||||.|.:.
Zfish   459 KLFVQDDKGKFNFDQTAVRNPETGELISSWYKGSETWDSKFSTIASSYEECRAECVGLYLCLSKQ 523

  Fly   580 ILEIFGFKDKAEQDNIIYVNWLSLIWNGMGVALEMFNPKSKLWLQAHSRARFVIMKVLLEAGEGL 644
            :|.|||.:.: :.:.::|||||:::..|: :.||.:.|:||.|.|||.:|||||::|||||||||
Zfish   524 VLSIFGHEGE-DAEEVLYVNWLNMVRAGL-LGLEFYTPESKSWRQAHMQARFVILRVLLEAGEGL 586

  Fly   645 VKVEE---TEKGKNLLLTVDRSKIDTVGRKALGDFLTKLQVYKSTADIEAASKMYEHYSKVDESG 706
            |.|:|   |:...:.::|:|||||:|||:.|:..||.||||||||||:|....:||.||.|...|
Zfish   587 VCVKECTGTDGRPDAVITLDRSKINTVGKSAIQRFLCKLQVYKSTADVEGGRALYEGYSAVTSDG 651

  Fly   707 SHPWAKWRDICLAHKKPRMILVQANTAIGQDQKVQLKTYEPTHEGYIQSWVERYP--NTDIDDLL 769
            :|.:.:.|:..|..|:.|.:.|||||.| :|..|:|..||.:.||.|||::||:|  :.::|..|
Zfish   652 AHDFLRLRETVLLRKEARKMFVQANTFI-KDDAVELIEYEGSAEGLIQSFIERFPDDSEEVDAQL 715

  Fly   770 ESIVEKD 776
            ..:..||
Zfish   716 LEMTRKD 722

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DppIII	NP_731237.1	Peptidase_M49	207..760	CDD:460976	293/564 (52%)
dpp3	NP_001002683.1	Peptidase_M49	143..704	CDD:460976	293/563 (52%)