DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9601 and Aptx

DIOPT Version :9

Sequence 1:	NP_649792.3	Gene:	CG9601 / 40994	FlyBaseID:	FBgn0037578	Length:	523	Species:	Drosophila melanogaster
Sequence 2:	XP_017448660.1	Gene:	Aptx / 259271	RGDID:	628740	Length:	343	Species:	Rattus norvegicus

Alignment Length:	232	Identity:	64/232 - (27%)
Similarity:	107/232 - (46%)	Gaps:	52/232 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 RICTLKPTEPEHHSI---HLTAGENFVGRSRETGIRDSKCSKRQIQLQVDLKKAVVSLKVLGVNP 82
            |:|.|...:..|..|   ||.|  ..:|||.||.|.|.|||::|:||:.:..|..|::|.:||||
  Rat    16 RVCWLVRQDCWHQRIKLPHLEA--VVIGRSPETKITDKKCSRQQVQLKAECNKRYVNVKQMGVNP 78

  Fly    83 CGVNGLMLMQNGERELKHGDLVEIVYGRH----QFEVVFNPP---------PEYDKEK------A 128
            ..::.:::.::.|.:|..|.::.:|...:    :||.|...|         |:.|.::      |
  Rat    79 TSIDEVVIGKDREMKLLPGQVLHMVNELYPYMVEFEEVAESPNVTQRKRKRPDCDSQEMEAEAGA 143

  Fly   129 EPLSTTLSP---SEKSERWDSSGNGKLVIFTSVGVKGS---EKIAGY-DMDGTIIKTKSGLVFPK 186
            .|...::||   ...:.:.:|.|:      .|.|:|.|   .|:..| |....:||.|    :||
  Rat   144 SPSQCSVSPKTGKHGAAKEESLGH------WSQGLKISMKDPKMQVYKDDQVVVIKDK----YPK 198

  Fly   187 NTDDW-----------QIIFPEVPEKLKNLHKDGFKI 212
            ....|           :::..|..|.||::|..|.|:
  Rat   199 ARHHWLVLPWASISSLKVVTSEHLELLKHMHAVGEKV 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9601	NP_649792.3	PNK-3'Pase	9..522	CDD:130724	64/232 (28%)
		FHA	26..115	CDD:238017	30/95 (32%)
		HAD_like	170..288	CDD:119389	14/54 (26%)
		NK	367..>440	CDD:302627
Aptx	XP_017448660.1	FHA	<38..112	CDD:238017	24/73 (33%)
		aprataxin_related	165..266	CDD:238609	21/81 (26%)
		zf-C2HE	285..341	CDD:292895
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	56	1.000	Domainoid score	I10742
eggNOG	1	0.900	-	-		E1_COG0241
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810