Protein Alignment PNKP and PNKP

DIOPT Version :10

• Sequence 1: NP_649792.3
• Gene: PNKP / 40994
• FlyBaseID: FBgn0037578
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: XP_320361.5
• Gene: PNKP / 1280513
• VectorBaseID: AGAMI1_010536
• Length: 633
• Species: Anopheles gambiae
• Alignment Length: 620
• Identity: 248/620 - (40%)
• Similarity: 341/620 - (55%)
• Gaps: 108/620 - (17%)

  Fly     7 LNRSVGKAGKDVAARICTLKPTEPEHHSIHLTAGENFVGRSRETGIRDSKCSKRQIQLQVDLKKA 71
            :|||.....|  ..:.|.:||..||:..|.:...:..||||.||.|:|..||::|:.|:.:|::.
Mosquito    19 VNRSCKNMSK--ILKECVIKPLSPEYLPIRINTEQTMVGRSPETQIQDELCSRKQVCLKANLEQG 81

  Fly    72 VVSLKVLGVNPCGVNGLMLMQNGERELKHGDLVEIVYG--RHQFEVVFNPP-------PEYDKEK 127
            .|.:|.||:||..:||..|.:|...|..|||::|:|.|  ::.|:.::.|.       |:..|:.
Mosquito    82 YVLVKSLGLNPSVLNGKELKRNIGYEAVHGDILELVPGMYKYVFDFIYEPSTSEEEKGPQTSKKS 146

  Fly   128 AEPLST----------------------TLSPSEKSE---------------------------- 142
            :...|:                      ..||.|::|
Mosquito   147 SSASSSGNRSGSSRTNASSTSNGKRSREESSPKEETEFVPKVEKTSKRSSSGKRSSPSRSNASNS 211

  Fly   143 -------------------------------------RWDSSGNGKLVIFTSVGVKGSEKIAGYD 170
                                                 ||::|.:..|.||||.||..|||:|.||
Mosquito   212 GSEKRSREESSPKRSKQAASPVPVEKRKLSLAPTTEGRWEASDDKLLHIFTSAGVMASEKVAAYD 276

  Fly   171 MDGTIIKTKSGLVFPKNTDDWQIIFPEVPEKLKNLHKDGFKICLFTNQGGIARGKINLDDFKVKI 235
            ||||:||||||.||||:.|||||.|.|||.|||:||::|:|:.:||||.||.:||:.::||:.||
Mosquito   277 MDGTLIKTKSGNVFPKSIDDWQIAFAEVPAKLKSLHRNGYKLVIFTNQAGIGKGKVRIEDFRQKI 341

  Fly   236 KHIVAKLGVPIQVFIAIGDGFYRKPLTGMWQHL--KSEMNDGVEIQEDRCFFVGDAAGRPETGKG 298
            :.:|.|||||:||||:.|.|.||||.|||||.|  :.:.:|||:|...|.|:|||||||||. |.
Mosquito   342 ESLVRKLGVPMQVFISTGSGKYRKPRTGMWQTLCDRQQKDDGVQIDRARSFYVGDAAGRPEL-KK 405

  Fly   299 ATKRRKDHSLVDRLFAANVGISFYTPEVHFLGKQVEQWNKPDFEP-----TSVQDQVSLLDPDDL 358
            ..||:||||..|||.|.||||.|.|||.||.......|.||:|:|     .:|.:  .||.|...
Mosquito   406 PVKRKKDHSSADRLLALNVGIRFLTPEEHFQNLPEMPWTKPEFDPREACRLAVNE--PLLVPAGA 468

  Fly   359 TLDDHPCEMVIMVGLPGSGKSHFCSSFFQPRGYKIVNADTLGSTQNCLTACKRFLDSGQSCVVDN 423
            :|.....|:::|||.||||||||......|:||.|||.|||||.|.|:...:..|..|:|..|||
Mosquito   469 SLTGSVQEVIVMVGFPGSGKSHFVREHLAPKGYDIVNRDTLGSWQKCVVQMELSLRQGKSVAVDN 533

  Fly   424 TNVDAASRKKFLQLASEKMIPCRCLVMNVPVAQVKHNIAFRELSDSARTKIKDMVFNMMKKKYQE 488
            .:.|..|||:::.:|:...:|.||.:|:|.....:||..|||::|.:.:.|.::|||..|.|:||
Mosquito   534 LSPDVESRKRYVLVANRAKVPVRCFLMDVGYKHARHNNEFREMTDRSHSTISELVFNSYKSKFQE 598

  Fly   489 PALDEGFISIHKVNFKPNFADEKQEKLYKMYLVEK 523
            |.:.|||..|.||.|.|.||.:..|.||:|:|:||
Mosquito   599 PTVAEGFTEIVKVKFVPKFASKSHEDLYRMFLLEK 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PNKP	NP_649792.3	PNK-3'Pase	9..522	CDD:130724	245/615 (40%)
PNKP	XP_320361.5	None