DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arl2 and Trim23

DIOPT Version :9

Sequence 1:	NP_476886.1	Gene:	Arl2 / 40993	FlyBaseID:	FBgn0004908	Length:	184	Species:	Drosophila melanogaster
Sequence 2:	XP_008758905.1	Gene:	Trim23 / 81002	RGDID:	621587	Length:	601	Species:	Rattus norvegicus

Alignment Length:	171	Identity:	69/171 - (40%)
Similarity:	99/171 - (57%)	Gaps:	9/171 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 EMRILLLGLDNAGKTTILKRFNGEPIDTISPTLGFNIKTLEHNGYTLNMWDVGGQKSLRSYWRNY 80
            |:|::.||||.|||||||.:...:......||:|||::|:|:......:|||||:..||..|::|
  Rat   431 EIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHY 495

  Fly    81 FESTDGLVWVVDSADRMRLESCGQELQVLLQEERLAGATLLVLCNKQDLPGALSSNEIKEILHLE 145
            :.:|..:|:||||:.|.|:.....||..||.|:.|..|.||:..||||:.||||..||.|:|.|.
  Rat   496 YLNTQAVVFVVDSSHRDRISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLH 560

  Fly   146 DITT-HHWLVAGVSAVTGEKLLSSMDWL--------IADIA 177
            .:.. ..|.:.|..|.:|..|...:|||        :.|:|
  Rat   561 KLCCGRSWYIQGCDARSGMGLYEGLDWLSRQLVAAGVLDVA 601

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arl2	NP_476886.1	Arl2	3..175	CDD:206720	67/167 (40%)
Trim23	XP_008758905.1	zf-RING_UBOX	58..100	CDD:290181
		BBOX	152..195	CDD:237988
		BBOX	200..246	CDD:197662
		BBC	253..397	CDD:128778
		ARD1	433..601	CDD:206723	67/167 (40%)
		Ras	433..592	CDD:278499	66/158 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910