DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arl2 and TRIM23

DIOPT Version :9

Sequence 1:	NP_476886.1	Gene:	Arl2 / 40993	FlyBaseID:	FBgn0004908	Length:	184	Species:	Drosophila melanogaster
Sequence 2:	NP_001647.1	Gene:	TRIM23 / 373	HGNCID:	660	Length:	574	Species:	Homo sapiens

Alignment Length:	171	Identity:	69/171 - (40%)
Similarity:	99/171 - (57%)	Gaps:	9/171 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 EMRILLLGLDNAGKTTILKRFNGEPIDTISPTLGFNIKTLEHNGYTLNMWDVGGQKSLRSYWRNY 80
            |:|::.||||.|||||||.:...:......||:|||::|:|:......:|||||:..||..|::|
Human   404 EIRVVTLGLDGAGKTTILFKLKQDEFMQPIPTIGFNVETVEYKNLKFTIWDVGGKHKLRPLWKHY 468

  Fly    81 FESTDGLVWVVDSADRMRLESCGQELQVLLQEERLAGATLLVLCNKQDLPGALSSNEIKEILHLE 145
            :.:|..:|:||||:.|.|:.....||..||.|:.|..|.||:..||||:.||||..||.|:|.|.
Human   469 YLNTQAVVFVVDSSHRDRISEAHSELAKLLTEKELRDALLLIFANKQDVAGALSVEEITELLSLH 533

  Fly   146 DITT-HHWLVAGVSAVTGEKLLSSMDWL--------IADIA 177
            .:.. ..|.:.|..|.:|..|...:|||        :.|:|
Human   534 KLCCGRSWYIQGCDARSGMGLYEGLDWLSRQLVAAGVLDVA 574

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arl2	NP_476886.1	Arl2	3..175	CDD:206720	67/167 (40%)
TRIM23	NP_001647.1	mRING-HC-C3HC3D_TRIM23_C-IX	28..77	CDD:319559
		Bbox2_TRIM23_C-IX_rpt1	123..172	CDD:380831
		Bbox2_TRIM23_C-IX_rpt2	174..223	CDD:380832
		BBC	226..370	CDD:128778
		ARF-like	390..574		68/169 (40%)
		ARD1	406..574	CDD:206723	67/167 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910