Protein Alignment Poxm and PAX4

DIOPT Version :10

• Sequence 1: NP_001036687.1
• Gene: Poxm / 40990
• FlyBaseID: FBgn0003129
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_001353039.1
• Gene: PAX4 / 5078
• HGNCID: 8618
• Length: 351
• Species: Homo sapiens
• Alignment Length: 165
• Identity: 83/165 - (50%)
• Similarity: 106/165 - (64%)
• Gaps: 10/165 - (6%)

  Fly    13 VNQLGGVFVNGRPLPNATRMRIVELARLGIRPCDISRQLRVSHGCVSKILARYHETGSILPGAIG 77
            :|||||:||||||||..||.:||.||..|:|||||||.|:||:|||||||.||:.||.:.|..||
Human     9 MNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLEPKGIG 73

  Fly    78 GSKPRVTTPKVVNYIRELKQRDPGIFAWEIRDRLLSEGICDKTNVPSVSSISRILRNKLGSLG-- 140
            |||||:.||.||..|.:||...|.:|||||:.:|.:||:|.:...||||||:|:||......|
Human    74 GSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRVLRALQEDQGLP 138

  Fly   141 --HQHTPGTVM------GSGSSSGGGSVSSNGGQN 167
              ...:|..:.      .|||.:..|:....|.:|
Human   139 CTRLRSPAVLAPAVLTPHSGSETPRGTHPGTGHRN 173

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Poxm	NP_001036687.1	PAX	10..133	CDD:128645	73/119 (61%)
PAX4	NP_001353039.1	PAX	5..129	CDD:128645	73/119 (61%)
		Homeodomain	172..227	CDD:459649	1/2 (50%)