Protein Alignment Poxm and DUXA

DIOPT Version :10

• Sequence 1: NP_001036687.1
• Gene: Poxm / 40990
• FlyBaseID: FBgn0003129
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_001012747.1
• Gene: DUXA / 503835
• HGNCID: 32179
• Length: 204
• Species: Homo sapiens
• Alignment Length: 168
• Identity: 38/168 - (22%)
• Similarity: 66/168 - (39%)
• Gaps: 33/168 - (19%)

  Fly    22 NGRPLPN-ATRMRI-----VELARLGIRPCDISRQLRVSHGCVSKILARYHET----GSILPGAI 76
            |.:|.|. ||:.::     .|.:|:.|    ..:..|..||...:..|...|:    |...||..
Human    35 NQKPYPGYATKQKLALEINTEESRIQI----WFQNRRARHGFQKRPEAETLESSQSQGQDQPGVE 95

  Fly    77 GGSKP--RVTTPKVVNYIREL-----KQRDPGIFAWEIRDRLLSE-GICD-KTNVPSVSSISRIL 132
            ..|:.  |..|....:.:..|     |...|||   :.|:.|..| |:.: :..:...:..||:|
Human    96 FQSREARRCRTTYSASQLHTLIKAFMKNPYPGI---DSREELAKEIGVPESRVQIWFQNRRSRLL 157

  Fly   133 ----RNKLGSLGHQH---TPGTVMGSGSSSGGGSVSSN 163
                |..:.||..:.   .|..:.|:..:..|.:.:|:
Human   158 LQRKREPVASLEQEEQGKIPEGLQGAEDTQNGTNFTSD 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Poxm	NP_001036687.1	PAX	10..133	CDD:128645	31/133 (23%)
DUXA	NP_001012747.1	homeodomain	16..74	CDD:238039	11/42 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	73..101		6/27 (22%)
		Homeodomain	102..155	CDD:459649	11/55 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	163..204		6/33 (18%)