Protein Alignment Poxm and pax3

DIOPT Version :10

• Sequence 1: NP_001036687.1
• Gene: Poxm / 40990
• FlyBaseID: FBgn0003129
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: XP_012825755.1
• Gene: pax3 / 448464
• XenbaseID: XB-GENE-482740
• Length: 486
• Species: Xenopus tropicalis
• Alignment Length: 417
• Identity: 144/417 - (34%)
• Similarity: 181/417 - (43%)
• Gaps: 106/417 - (25%)

  Fly    11 GEVNQLGGVFVNGRPLPNATRMRIVELARLGIRPCDISRQLRVSHGCVSKILARYHETGSILPGA 75
            |.||||||||:|||||||..|.:|||:|..|||||.||||||||||||||||.||.|||||.|||
 Frog    37 GRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGA 101

  Fly    76 IGGSKPR-VTTPKVVNYIRELKQRDPGIFAWEIRDRLLSEGICDKTNVPSVSSISRILRNKLGSL 139
            ||||||: ||||:|...|.|.|:.:||:|:|||||:||.:|:||:..||||||||||||:|.|..
 Frog   102 IGGSKPKQVTTPEVEKKIEEFKRDNPGMFSWEIRDKLLKDGVCDRNTVPSVSSISRILRSKFGKG 166

  Fly   140 GHQ-----------------HTPGTVM-----GSGSSSGGGSVSSNGG------QNNGTSASNNI 176
            ..:                 |:...::     .|..|..|..:.|...      |....:.....
 Frog   167 DEEDIELDRKEQEESEKRAKHSIDGILRERAPASPESEEGSDIDSEPDLPLKRKQRRSRTTFTAE 231

  Fly   177 NLSNLGNPGGGPHHPHHHHHHQSAAAA---------------------ASAHHVHAHAH------ 214
            .|..|.......|:|..:...:.|..|                     |.|:.:.|..|
 Frog   232 QLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGAF 296

  Fly   215 --------AHAHLYNSIYQPYSAAAAYSMKTPCGS---PSP-PQGAGGQGSVPHPHQLRSVAAAA 267
                    ....|..:.|||.|...|.|  .|..:   |.| |..:..|.|:|...:..|.....
 Frog   297 PPAAMPALPTYQLSETSYQPTSIPQAVS--DPSNTVHRPQPLPPSSVHQSSLPSNPESSSAYCLP 359

  Fly   268 AAAHWPSSHSVSDILAHHQAVALRASCQVGVGVGGMGGMGSTVSPL-PMTP-SPVAGTAGGQP-- 328
            :..|..||::                             .|.|.|. |..| :|..|. |..|
 Frog   360 SGRHGFSSYT-----------------------------DSFVPPSGPSNPMNPAIGN-GLSPQV 394

  Fly   329 --LLDCEGGAGQQSPYNYYMYFQNGGM 353
              ||...||...|...:|.:....||:
 Frog   395 MGLLTNHGGVPHQPQTDYALSPLTGGL 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Poxm	NP_001036687.1	PAX	10..133	CDD:128645	89/122 (73%)
pax3	XP_012825755.1	PAX	35..162	CDD:238076	91/124 (73%)
		Homeodomain	222..278	CDD:459649	6/55 (11%)
		Pax7	349..393	CDD:403540	12/73 (16%)