Protein Alignment Poxm and Pax9

DIOPT Version :10

• Sequence 1: NP_001036687.1
• Gene: Poxm / 40990
• FlyBaseID: FBgn0003129
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_001034628.1
• Gene: Pax9 / 362741
• RGDID: 1560838
• Length: 342
• Species: Rattus norvegicus
• Alignment Length: 403
• Identity: 168/403 - (41%)
• Similarity: 196/403 - (48%)
• Gaps: 134/403 - (33%)

  Fly     8 PQYGEVNQLGGVFVNGRPLPNATRMRIVELARLGIRPCDISRQLRVSHGCVSKILARYHETGSIL 72
            |.:|||||||||||||||||||.|:||||||:||||||||||||||||||||||||||:||||||
  Rat     3 PAFGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSIL 67

  Fly    73 PGAIGGSKPRVTTPKVVNYIRELKQRDPGIFAWEIRDRLLSEGICDKTNVPSVSSISRILRNKLG 137
            ||||||||||||||.||.:||..|||||||||||||||||::|:|||.|||||||||||||||:|
  Rat    68 PGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIG 132

  Fly   138 SLGHQHTPGTVMGSGSSSGGGSVSSNGGQNNGTSASNNINLSNLGNPGGGPHHPHHHHHHQSAAA 202
            :|..|                                             .|:..:..|..:...
  Rat   133 NLAQQ---------------------------------------------GHYDSYKQHQPAPQP 152

  Fly   203 AASAHHVHAHAHAHAHLYNSIYQPYSAAAAYSMKTPCGSPSPPQGAGGQGSVPHPHQLRSVAAAA 267
            |...:|::::.           .|.:|||| .:.||.|.|:.|      |||..|..
  Rat   153 ALPYNHIYSYP-----------SPITAAAA-KVPTPPGVPAIP------GSVALPRT-------- 191

  Fly   268 AAAHWPSSHSVSDILA---------------HHQAV-------------------------ALRA 292
                |||||||:|||.               |...|                         ||..
  Rat   192 ----WPSSHSVTDILGIRSITDQGVSDSSPYHSPKVEEWSSLGRNNFSAAAPHAVNGLEKGALEQ 252

  Fly   293 SCQVGVGVGGMGGMGSTVSPLPMTPSPVAGTAGGQPLLDCEGGAGQQSPYNYYMYFQNGGMHHHH 357
            ..:.|....|:..:.|.||...|.|.|.               ..|.|||..|....:|.:..|
  Rat   253 EAKYGQAPNGLPAVSSFVSASSMAPYPT---------------PAQVSPYMTYSAAPSGYVAGH- 301

  Fly   358 HHGGMMAAGATGL 370
               |...||:|.|
  Rat   302 ---GWQHAGSTPL 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Poxm	NP_001036687.1	PAX	10..133	CDD:128645	108/122 (89%)
Pax9	NP_001034628.1	PAX	6..131	CDD:238076	111/124 (90%)
		PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	7..63		51/55 (93%)
		RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381	82..130		38/47 (81%)
		Interaction with KDM5B. /evidence=ECO:0000250	168..189		12/27 (44%)