Protein Alignment Poxm and pax3a

DIOPT Version :10

• Sequence 1: NP_001036687.1
• Gene: Poxm / 40990
• FlyBaseID: FBgn0003129
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_571352.1
• Gene: pax3a / 30532
• ZFINID: ZDB-GENE-980526-52
• Length: 509
• Species: Danio rerio
• Alignment Length: 444
• Identity: 149/444 - (33%)
• Similarity: 188/444 - (42%)
• Gaps: 103/444 - (23%)

  Fly    11 GEVNQLGGVFVNGRPLPNATRMRIVELARLGIRPCDISRQLRVSHGCVSKILARYHETGSILPGA 75
            |.||||||||:|||||||..|.:|||:|..|||||.||||||||||||||||.||.|||||.|||
Zfish    36 GRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGA 100

  Fly    76 IGGSKPR-VTTPKVVNYIRELKQRDPGIFAWEIRDRLLSEGICDKTNVPSVSSISRILRNKLGSL 139
            ||||||: .|||.|...|.|.|:.:||:|:|||||:||.:||||:.||||||||||:||.|.|..
Zfish   101 IGGSKPKQSTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDGICDRNNVPSVSSISRMLRCKFGGN 165

  Fly   140 GHQ--------------------HTPGTVMG--SGSSSGGGSVSSNGG------QNNGTSASNNI 176
            |.:                    |:...::|  |..|..|..|.|..|      |....:.....
Zfish   166 GDEDEDDDEVEKREIEENERRAKHSIDGILGDRSSHSDEGSDVDSEPGLPLKRKQRRSRTTFTAE 230

  Fly   177 NLSNLGNPGGGPHHPHHHHHHQSAAAA---------------------ASAHHVHAHAH------ 214
            .|..|.......|:|..:...:.|..|                     |.|:.:.|..|
Zfish   231 QLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGF 295

  Fly   215 --------AHAHLYNSIYQPYSAAAAYSMKTPCGSPS--PPQGA--GGQGSVPHPHQLRSVAAAA 267
                    ....|.:|.|.|.|.:......:....|.  ||...  .|.||.|...:..|....:
Zfish   296 PPSAMSSLQPYQLADSPYPPSSISQVSEQPSTVHRPQPLPPTSVHQSGLGSGPGAQEGSSAYCLS 360

  Fly   268 AAAHWPSSHSVSDILAHHQAVALRASCQVGVGVGGMGGMGS-----------TVSPL-----PMT 316
            :..|..|.:|...:.|...|..:..|...|:....||.:..           .:|||     |.|
Zfish   361 SGRHGFSGYSDGYVAAPGHANPVNPSISNGLPSQVMGLLNPGAVPHQPQSDFALSPLTGGLEPST 425

  Fly   317 PSPVAGTAG-------GQPLLDCEGGAGQQSPYNY------------YMYFQNG 351
            ..|.:..:.       |.|.:.....:....|.:|            |.|.|.|
Zfish   426 GMPASCHSSQRLEALPGLPSMPALPSSQSYCPSSYSSPGYSVDHVASYQYSQYG 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Poxm	NP_001036687.1	PAX	10..133	CDD:128645	89/122 (73%)
pax3a	NP_571352.1	PAX	34..159	CDD:128645	89/122 (73%)
		Homeodomain	221..277	CDD:459649	6/55 (11%)
		Pax7	350..394	CDD:403540	8/43 (19%)