Protein Alignment Poxm and pax-3

DIOPT Version :10

• Sequence 1: NP_001036687.1
• Gene: Poxm / 40990
• FlyBaseID: FBgn0003129
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_496189.2
• Gene: pax-3 / 185022
• WormBaseID: WBGene00003939
• Length: 308
• Species: Caenorhabditis elegans
• Alignment Length: 264
• Identity: 97/264 - (36%)
• Similarity: 130/264 - (49%)
• Gaps: 37/264 - (14%)

  Fly    11 GEVNQLGGVFVNGRPLPNATRMRIVELARLGIRPCDISRQLRVSHGCVSKILARYHETGSILPGA 75
            |.||||||||:||||||...|..|:.:|:.||:||.|||||:||||.|||||.||.|||||.||.
 Worm    15 GRVNQLGGVFINGRPLPIHVRHAIISMAKKGIKPCHISRQLKVSHGAVSKILNRYAETGSISPGQ 79

  Fly    76 IGGS-KPRVTTPKVVNYIRELKQRDPGIFAWEIRDRLLSEGICDKTNVPSVSSISRILRNKLGSL 139
            |||| :.|:|...|...|......:|.:.|.|:||.|:.:.||.|.|.|:|.:|.|::.||  .:
 Worm    80 IGGSPRARLTVQAVEKEILIACDENPQMSAAELRDWLIHKDICTKGNAPTVPAIKRLIGNK--GV 142

  Fly   140 G---------HQHTPGTVMG--------SGSSSGGGSVSSN--GGQNNGTSASNNINLSNLGNPG 185
            |         ..::..:::|        |.|....||..||  ..:.|.||.:.. .|..|.|..
 Worm   143 GVPKKMERKRLSYSIDSILGISIDECSKSSSDDEEGSSPSNDASSRRNRTSFTAE-QLDVLENAF 206

  Fly   186 GGPHHPHHHHHHQ-SAAAAASAHHV---HAHAHAHAHLYNSIYQPY------SAAAAYSMKTPCG 240
            ....:||.:.... |.....|...:   .::..|.......:||.|      |:..:|    |..
 Worm   207 RADTYPHANARESISKETGLSEEKIMTWFSNRRARCRKNMPMYQQYNVQGFGSSPPSY----PTL 267

  Fly   241 SPSP 244
            .|||
 Worm   268 LPSP 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Poxm	NP_001036687.1	PAX	10..133	CDD:128645	67/122 (55%)
pax-3	NP_496189.2	PAX	13..141	CDD:238076	69/127 (54%)
		Homeodomain	188..244	CDD:459649	11/56 (20%)