DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ctr1B and Ctr1C

DIOPT Version :9

Sequence 1:	NP_649790.1	Gene:	Ctr1B / 40989	FlyBaseID:	FBgn0062412	Length:	174	Species:	Drosophila melanogaster
Sequence 2:	NP_651837.1	Gene:	Ctr1C / 43668	FlyBaseID:	FBgn0062411	Length:	270	Species:	Drosophila melanogaster

Alignment Length:	219	Identity:	70/219 - (31%)
Similarity:	100/219 - (45%)	Gaps:	54/219 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 HGSDDSTSTAKSCPMIMVFHAGHCERILWRGWVASTVTEFVLSALAIFLVSFLYEALKFLRQQL- 66
            ||..:  ..|....|.|.||.|..|.||::.|...:.....||.|.||:|:.|||||||.|:.|
  Fly    51 HGHHE--GGAHDMSMAMFFHTGDSETILFKFWRTESAMALTLSCLLIFMVAVLYEALKFFREWLF 113

  Fly    67 ------------------ARREA--------------RRASEQLAAEQRRKNEAPAAGGCCSEAP 99
                              ..|||              :::..|:.|.:.|....|........:|
  Fly   114 SWDRKRLAGGRDQYNRPRRYREANYNYNQPTYPPRTNQQSGTQVYAYRPRSPSMPPLQPPGRSSP 178

  Fly   100 LAE------------------PREQTYWQRLFASS-HIVQSLLNLLQIVISYLLMLIFMTFNYWL 145
            .|:                  |..:|...::|.|. ||:|:.|::||::||:||||:|||||.||
  Fly   179 QAQSSLILTQHTHHHVQENTPPAGRTTKLKVFCSGMHILQTFLHVLQVLISFLLMLVFMTFNVWL 243

  Fly   146 CLAVILGLGLGYFFFGWNKKNPDE 169
            |:||:||.|:||:.|...:.|..|
  Fly   244 CVAVLLGAGVGYYIFCAFRTNVQE 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ctr1B	NP_649790.1	Ctr	17..160	CDD:282057	64/194 (33%)
Ctr1C	NP_651837.1	SelP_N	<23..56	CDD:282453	2/6 (33%)
Ctr1C	NP_651837.1	Ctr	63..258	CDD:282057	64/194 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45435324
Domainoid	1	1.000	52	1.000	Domainoid score	I4266
eggNOG	1	0.900	-	-		E1_KOG3386
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	56	1.000	Inparanoid score	I2023
Isobase	1	0.950	-	0	Normalized mean entropy	S2329
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D130811at33392
OrthoFinder	1	1.000	-	-		FOG0000938
OrthoInspector	1	1.000	-	-		otm14791
orthoMCL	1	0.900	-	-		OOG6_104136
Panther	1	1.100	-	-	P	PTHR12483
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4018
SonicParanoid	0	0.000	Not matched by this tool.
	12	11.780