DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Coq2 and COQ2

DIOPT Version :9

Sequence 1:	NP_649789.1	Gene:	Coq2 / 40988	FlyBaseID:	FBgn0037574	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_056512.5	Gene:	COQ2 / 27235	HGNCID:	25223	Length:	421	Species:	Homo sapiens

Alignment Length:	314	Identity:	197/314 - (62%)
Similarity:	238/314 - (75%)	Gaps:	9/314 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 EPVKQQTPLQ--ELVSAA----KPYAQLMRIDRPIGTYLLFWPCAWSIALSADAGCWPDLTMLGL 120
            ||..:|..|.  .:|.:|    :||.:|||:|:||||:||:.||.|||.|:|:.||:||..||.|
Human   100 EPRGRQLSLSAAAVVDSAPRPLQPYLRLMRLDKPIGTWLLYLPCTWSIGLAAEPGCFPDWYMLSL 164

  Fly   121 FGTGALIMRGAGCTINDLWDKDIDAKVERTRLRPLASGQISQFDAIVFLSAQLSLGLLVLVQLNW 185
            |||||::||||||||||:||:|.|.||.||..||:|:|.||.|.:.|||..||:|.|.||:.||:
Human   165 FGTGAILMRGAGCTINDMWDQDYDKKVTRTANRPIAAGDISTFQSFVFLGGQLTLALGVLLCLNY 229

  Fly   186 QSILLGASSLGLVITYPLMKRVTYWPQLVLGMAFNWGALLGWCATQGSVNLAACLPLYLSGVCWT 250
            .||.|||.||.||||||||||::|||||.||:.|||||||||.|.:||.:.:.|||||.|||.||
Human   230 YSIALGAGSLLLVITYPLMKRISYWPQLALGLTFNWGALLGWSAIKGSCDPSVCLPLYFSGVMWT 294

  Fly   251 IVYDTIYAHQDKLDDLQIGVKSTALRFGENTKVWLSGFTAAMLTGLSAAGWACDQTVPYYAAVGV 315
            ::||||||||||.||:.||:||||||||||||.|||||:.|||..||..|....||.|||||:|.
Human   295 LIYDTIYAHQDKRDDVLIGLKSTALRFGENTKPWLSGFSVAMLGALSLVGVNSGQTAPYYAALGA 359

  Fly   316 VGAHLVQQIYSLNIDNPSDCAKKFISNHQVGLILFLGIVLGTL---LKSDESKK 366
            |||||..|||:|:|..|.||..|||||..:|||:|||||||.|   .|:|::||
Human   360 VGAHLTHQIYTLDIHRPEDCWNKFISNRTLGLIVFLGIVLGNLWKEKKTDKTKK 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Coq2	NP_649789.1	PT_UbiA	73..358	CDD:294241	188/288 (65%)
COQ2	NP_056512.5	PT_UbiA	118..403	CDD:294241	186/284 (65%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158976
Domainoid	1	1.000	339	1.000	Domainoid score	I1101
eggNOG	1	0.900	-	-		E1_COG0382
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69192
Inparanoid	1	1.050	396	1.000	Inparanoid score	I1968
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57870
OrthoDB	1	1.010	-	-		D1343847at2759
OrthoFinder	1	1.000	-	-		FOG0004404
OrthoInspector	1	1.000	-	-		oto88501
orthoMCL	1	0.900	-	-		OOG6_101249
Panther	1	1.100	-	-	LDO	PTHR11048
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R232
SonicParanoid	1	1.000	-	-		X3123
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800