DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Coq2 and ppt1

DIOPT Version :9

Sequence 1:	NP_649789.1	Gene:	Coq2 / 40988	FlyBaseID:	FBgn0037574	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_593219.2	Gene:	ppt1 / 2543235	PomBaseID:	SPAC56F8.04c	Length:	360	Species:	Schizosaccharomyces pombe

Alignment Length:	359	Identity:	152/359 - (42%)
Similarity:	212/359 - (59%)	Gaps:	33/359 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 MLPR-QPARVLI--GDWST---WDKSRLQDVCSRSSSTATEPVKQQTPLQELVSAAKP------- 79
            :||: .|||..:  ..||.   :...:::.:..|::|:     ...||  .|:|.:|.
pombe     5 LLPQPSPARYFLRTPSWSAVAIFQAVKIKPLQLRTNSS-----NSVTP--NLISPSKKSWKDLFS 62

  Fly    80 -----YAQLMRIDRPIGTYLLFWPCAWSIALSA---DAGCWPDLTMLGLFGTGALIMRGAGCTIN 136
                 ||::.|...|.|||||:.||.|||.::|   |:.......||.|||.|:.:||.|||.||
pombe    63 KRWQYYAEISRAGSPTGTYLLYSPCTWSILMAAYAYDSSLVNVTKMLALFGVGSFLMRSAGCVIN 127

  Fly   137 DLWDKDIDAKVERTRLRPLASGQISQFDAIVFLSAQLSLGLLVLVQLNWQSILLGASSLGLVITY 201
            ||||:::||||||::.||||||::|...||..||.||:..|.:|:|||..:|.||.:||..|..|
pombe   128 DLWDRELDAKVERSKSRPLASGKLSVRQAISLLSVQLTASLGILLQLNPYTIKLGVASLVPVCIY 192

  Fly   202 PLMKRVTYWPQLVLGMAFNWGALLGWCATQGS--VNLAACLPLYLSGVCWTIVYDTIYAHQDKLD 264
            |.|||:||:||:|||:.|.:||::||.|..|.  :|.:...|||||.:.|.::||||||||||.|
pombe   193 PAMKRITYYPQVVLGLTFGYGAVMGWPALAGEACMNWSVVAPLYLSTISWIVLYDTIYAHQDKRD 257

  Fly   265 DLQIGVKSTALRFGENTKVWLSGFTAAMLTGLSAAGWACDQTVPYYAAVGVVGA--HLVQQIYSL 327
            |::..:.|||||||:|||..|.|..|..:..|:.||....|. |.:..:||.||  .|...||.:
pombe   258 DVKANIYSTALRFGDNTKPVLCGLAALQIATLATAGIMNGQG-PVFYTLGVAGAAYRLSSMIYKV 321

  Fly   328 NIDNPSDCAKKFISNHQVGLILFLGIVLGTLLKS 361
            ::|:|.||.:.|..|...|.::...|.|..|.||
pombe   322 DLDDPKDCFRWFKRNSNTGYLVAAAIALDWLAKS 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Coq2	NP_649789.1	PT_UbiA	73..358	CDD:294241	138/303 (46%)
ppt1	NP_593219.2	ubiA_proteo	65..352	CDD:130539	135/287 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	225	1.000	Domainoid score	I526
eggNOG	1	0.900	-	-		E1_COG0382
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69192
Inparanoid	1	1.050	259	1.000	Inparanoid score	I752
OMA	1	1.010	-	-		QHG57870
OrthoFinder	1	1.000	-	-		FOG0004404
OrthoInspector	1	1.000	-	-		oto100507
orthoMCL	1	0.900	-	-		OOG6_101249
Panther	1	1.100	-	-	LDO	PTHR11048
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R232
SonicParanoid	1	1.000	-	-		X3123
TreeFam	1	0.960	-	-
	13	12.950