DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Coq2 and coq2

DIOPT Version :9

Sequence 1:	NP_649789.1	Gene:	Coq2 / 40988	FlyBaseID:	FBgn0037574	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_001082955.1	Gene:	coq2 / 100037331	ZFINID:	ZDB-GENE-070410-84	Length:	378	Species:	Danio rerio

Alignment Length:	307	Identity:	198/307 - (64%)
Similarity:	240/307 - (78%)	Gaps:	6/307 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 LVSAA----KPYAQLMRIDRPIGTYLLFWPCAWSIALSADAGCWPDLTMLGLFGTGALIMRGAGC 133
            :|:||    :||.:|||:|:||||:||:.||.|||.|:||.||.|||.||.|||.|||:||||||
Zfish    71 IVNAAPASVQPYLRLMRLDKPIGTWLLYLPCTWSIGLAADPGCLPDLRMLTLFGVGALLMRGAGC 135

  Fly   134 TINDLWDKDIDAKVERTRLRPLASGQISQFDAIVFLSAQLSLGLLVLVQLNWQSILLGASSLGLV 198
            ||||:||||.|.||.||..||:|||.|::|.|:|||..||||.|.||:.||:.||.|||:||.||
Zfish   136 TINDMWDKDFDKKVSRTATRPIASGDITRFQALVFLGGQLSLALGVLLSLNYYSIALGAASLSLV 200

  Fly   199 ITYPLMKRVTYWPQLVLGMAFNWGALLGWCATQGSVNLAACLPLYLSGVCWTIVYDTIYAHQDKL 263
            :|||||||:|||||.:||:.|||||||||.|.:||.:.:.|||||:|||.||::||||||||||.
Zfish   201 VTYPLMKRITYWPQFILGLTFNWGALLGWSAVKGSCDWSVCLPLYVSGVMWTLIYDTIYAHQDKD 265

  Fly   264 DDLQIGVKSTALRFGENTKVWLSGFTAAMLTGLSAAGWACDQTVPYYAAVGVVGAHLVQQIYSLN 328
            |||::|||||||||.||||:||||||.|||:||..||...|||.|||.||..|..||..||||::
Zfish   266 DDLKVGVKSTALRFQENTKLWLSGFTGAMLSGLLLAGVNADQTAPYYCAVSAVALHLAHQIYSVD 330

  Fly   329 IDNPSDCAKKFISNHQVGLILFLGIVLGTLLK--SDESKKQRQSSLT 373
            |:.|.||.|||.||..:||:||||||.|.|.|  |||..:.:.:|::
Zfish   331 INRPEDCWKKFASNRNLGLLLFLGIVAGNLWKKRSDEQYETQLNSIS 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Coq2	NP_649789.1	PT_UbiA	73..358	CDD:294241	192/288 (67%)
coq2	NP_001082955.1	PLN02809	76..361	CDD:178405	189/284 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594951
Domainoid	1	1.000	356	1.000	Domainoid score	I948
eggNOG	1	0.900	-	-		E1_COG0382
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69192
Inparanoid	1	1.050	411	1.000	Inparanoid score	I1839
OMA	1	1.010	-	-		QHG57870
OrthoDB	1	1.010	-	-		D1343847at2759
OrthoFinder	1	1.000	-	-		FOG0004404
OrthoInspector	1	1.000	-	-		oto39929
orthoMCL	1	0.900	-	-		OOG6_101249
Panther	1	1.100	-	-	LDO	PTHR11048
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R232
SonicParanoid	1	1.000	-	-		X3123
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800