DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7483 and EIF4A-III

DIOPT Version :9

Sequence 1:	NP_649788.2	Gene:	CG7483 / 40987	FlyBaseID:	FBgn0037573	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_188610.1	Gene:	EIF4A-III / 821513	AraportID:	AT3G19760	Length:	408	Species:	Arabidopsis thaliana

Alignment Length:	397	Identity:	310/397 - (78%)
Similarity:	353/397 - (88%)	Gaps:	0/397 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RKNAQAEDLSNVEFETSEDVEVIPTFNAMNLKEELLRGIYAYGFEKPSAIQQRSITPIVKGRDVI 67
            |:...|.|...:.|||::.:|.|.:||.|.:||::|||:|.||||||||||||::.||::|||||
plant    12 RRGGGAMDDDKLVFETTDGIEPITSFNDMGIKEDVLRGVYEYGFEKPSAIQQRAVMPILQGRDVI 76

  Fly    68 AQAQSGTGKTATFSISILQSLDTTLRETQVLCLSPTRELAVQIQKVILALGDMMNVQCHVCIGGT 132
            ||||||||||:..::|:.|.:||:.||.|.|.||||||||.|.:|.|.|:|...|:|.|.||||.
plant    77 AQAQSGTGKTSMIALSVCQVVDTSSREVQALILSPTRELATQTEKTIQAIGLHANIQAHACIGGN 141

  Fly   133 NLGEDIRKLDYGQHIVSGTPGRVFDMIKRRVLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLP 197
            ::|||||||::|.|:||||||||.||||||.|||||||:|:|||:||||::|||:||||||||||
plant   142 SVGEDIRKLEHGVHVVSGTPGRVCDMIKRRSLRTRAIKLLILDESDEMLSRGFKDQIYDVYRYLP 206

  Fly   198 PATQVVLISATLPHEILEMTSKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDT 262
            |..||.|:|||||||||||||||||:|::|||||||||||||||||||||:||||||||||||||
plant   207 PDLQVCLVSATLPHEILEMTSKFMTEPVKILVKRDELTLEGIKQFFVAVEKEEWKFDTLCDLYDT 271

  Fly   263 LTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERDEIMKEFRAGQSRVLITTDVWAR 327
            |||||||||||||||||:|:||||..|||||||||||||||||.||.|||:|.||||||||||||
plant   272 LTITQAVIFCNTKRKVDYLSEKMRSHNFTVSSMHGDMPQKERDAIMNEFRSGDSRVLITTDVWAR 336

  Fly   328 GIDVQQVSLVINYDLPNNRELYIHRIGRSGRFGRKGVAINFVKSDDIRILRDIEQYYSTQIDEMP 392
            |||||||||||||||||||||||||||||||||||||||||||||||:|||||||||||||||||
plant   337 GIDVQQVSLVINYDLPNNRELYIHRIGRSGRFGRKGVAINFVKSDDIKILRDIEQYYSTQIDEMP 401

  Fly   393 MNVADLI 399
            |||||||
plant   402 MNVADLI 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7483	NP_649788.2	PTZ00424	4..399	CDD:185609	307/394 (78%)
EIF4A-III	NP_188610.1	PTZ00424	32..408	CDD:185609	302/375 (81%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	234	1.000	Domainoid score	I631
eggNOG	1	0.900	-	-		E2759_KOG0328
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5602
Inparanoid	1	1.050	632	1.000	Inparanoid score	I196
OMA	1	1.010	-	-		QHG53631
OrthoDB	1	1.010	-	-		D726081at2759
OrthoFinder	1	1.000	-	-		FOG0000304
OrthoInspector	1	1.000	-	-		oto3187
orthoMCL	1	0.900	-	-		OOG6_101114
Panther	1	1.100	-	-	LDO	PTHR47958
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X250
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840