DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7483 and CG9630

DIOPT Version :9

Sequence 1:	NP_649788.2	Gene:	CG7483 / 40987	FlyBaseID:	FBgn0037573	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_649777.1	Gene:	CG9630 / 40974	FlyBaseID:	FBgn0037561	Length:	613	Species:	Drosophila melanogaster

Alignment Length:	378	Identity:	115/378 - (30%)
Similarity:	204/378 - (53%)	Gaps:	31/378 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 LKEELLRGIYAYGFEKPSAIQQRSITPIVKGRDVIAQAQSGTGKTATFSISILQSLDTTLRETQ- 96
            |.:.:|:.:.::||::.:.:|..:|..::..:||.|:|.:|:|||..|.:.:|:.|....:||.
  Fly    14 LSDAVLQVVQSFGFQQMTPVQTAAIPLLLARKDVSAEAVTGSGKTLAFLVPMLEILQRRHKETPW 78

  Fly    97 ------VLCLSPTRELAVQIQKVI---LALGDMMNVQCHVCIGGTNLGEDIRKLDYGQH-IVSGT 151
                  .|.:|||||||.||.:|:   |...|:.::...:.:||.::.|||..|..... |:..|
  Fly    79 GPKEIGALVISPTRELARQISEVLAQFLEHEDLEHLNQQLIVGGNSIEEDIATLRRETPCILVCT 143

  Fly   152 PGRVFDMIKRR------VLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLP 210
            |||:.|:.:|:      ..:.::::.|||||||.:|:.|||..:.::..|||...:..|.|||..
  Fly   144 PGRLEDLFQRKGDDLNLAAQVKSLEFLVLDEADRLLDLGFKTSVNNILGYLPRQRRTGLFSATQT 208

  Fly   211 HEILEMTSKFMTDPIRILVKRDEL--TLEGIKQFFVAVEREEWKFDTLCDLYDT--LTITQAVIF 271
            .|:.::....:.:|:.:.||....  |...::.|:..|| .|.||..|.:...:  ..|.:.::|
  Fly   209 TEVTDLIRAGLRNPVLVSVKEKASVNTPARLQNFYRIVE-PELKFVALLEFLSSPATVIGKVMVF 272

  Fly   272 CNTKRKVDWLTEKMRE--ANFTVSSMHGDMPQKERDEIMKEFRAGQSRVLITTDVWARGIDVQQV 334
            ..|...|::..|.:..  ...||..:||.|..| |..::::||.....||:.|||.|||:||.::
  Fly   273 FPTCACVEYWAEALPPLLPKRTVLGIHGKMKNK-RANVVEKFRNTPQAVLLCTDVLARGLDVPEI 336

  Fly   335 SLVINYDLPNNRELYIHRIGRSGRFGRKGVAINF-VKSDD-----IRILRDIE 381
            ..|:.:|.|:....::||:||:.|.|.:|.|:.| :.|:|     ::|.:.:|
  Fly   337 EWVVQWDPPSTASSFVHRVGRTARQGNEGNALVFLLPSEDAYVHFLKINQKVE 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7483	NP_649788.2	PTZ00424	4..399	CDD:185609	115/378 (30%)
CG9630	NP_649777.1	DEADc	6..226	CDD:238167	65/211 (31%)
		DEXDc	22..232	CDD:214692	65/209 (31%)
		HELICc	239..370	CDD:238034	42/132 (32%)
		DUF4217	411..470	CDD:290667
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451683
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930