DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7483 and CG7878

DIOPT Version :9

Sequence 1:	NP_649788.2	Gene:	CG7483 / 40987	FlyBaseID:	FBgn0037573	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_649767.1	Gene:	CG7878 / 40959	FlyBaseID:	FBgn0037549	Length:	703	Species:	Drosophila melanogaster

Alignment Length:	379	Identity:	133/379 - (35%)
Similarity:	209/379 - (55%)	Gaps:	32/379 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 ELLRGIYAYGFEKPSAIQQRSITPIVKGRDVIAQAQSGTGKTATFSI--SILQSLDTTLRETQ-- 96
            ::|..|...||.|||.||.::...:::|.|:|..||:|||||..|.:  .|.....:|.|.|:
  Fly   293 DMLEEITKMGFSKPSPIQSQAWPILLQGHDMIGIAQTGTGKTLAFLLPGMIHTEYQSTPRGTRGG 357

  Fly    97 --VLCLSPTRELAVQIQKVILALGDMMNVQCH-------VCI-GGTNLGEDIRKLDYGQHIVSGT 151
              ||.|:||||||:||:         |.|:.:       ||: ||.|....|..|:.|..|:..|
  Fly   358 ANVLVLAPTRELALQIE---------MEVKKYSFRGMKAVCVYGGGNRNMQISDLERGAEIIICT 413

  Fly   152 PGRVFDMIKRRVLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEM 216
            |||:.|:|...|:....|..|||||||.||:.||:.||..|...:.|..|.::.|||.|..:..:
  Fly   414 PGRLNDLIMANVIDVSTITYLVLDEADRMLDMGFEPQIRKVMLDIRPDRQTIMTSATWPPGVRRL 478

  Fly   217 TSKFMTDPIRILV-KRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTIT-QAVIFCNTKRKVD 279
            ...:|.:||::.| ..|......:||....:|.:..||:|:......::.| :.:|||..|.:.|
  Fly   479 AQSYMKNPIQVCVGSLDLAATHSVKQIIKLMEDDMDKFNTITSFVKNMSSTDKIIIFCGRKVRAD 543

  Fly   280 WLTEKMREANFTVSSMHGDMPQKERDEIMKEFRAGQSRVLITTDVWARGIDVQQVSLVINYDLPN 344
            .|:.::....|....:||:..|.:|::.:.:.::|..|:|:.|||.:||:|::.::.|||||.|:
  Fly   544 DLSSELTLDGFMTQCIHGNRDQMDREQAIADIKSGVVRILVATDVASRGLDIEDITHVINYDFPH 608

  Fly   345 NRELYIHRIGRSGRFGRKGVAINFVKSDD-------IRILRDIEQYYSTQIDEM 391
            |.|.|:||:||:||.||:|.:|:|...:|       |.||::.||....::..|
  Fly   609 NIEEYVHRVGRTGRAGRQGTSISFFTREDWAMAKELIEILQEAEQEVPDELHNM 662

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7483	NP_649788.2	PTZ00424	4..399	CDD:185609	133/379 (35%)
CG7878	NP_649767.1	KH-I	92..150	CDD:238053
		DEADc	288..489	CDD:238167	77/204 (38%)
		DEXDc	298..505	CDD:214692	79/215 (37%)
		Helicase_C	514..624	CDD:278689	39/109 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451503
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR47958
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940