DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7483 and SPAC1F5.10

DIOPT Version :9

Sequence 1:	NP_649788.2	Gene:	CG7483 / 40987	FlyBaseID:	FBgn0037573	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_592863.1	Gene:	SPAC1F5.10 / 2541602	PomBaseID:	SPAC1F5.10	Length:	394	Species:	Schizosaccharomyces pombe

Alignment Length:	391	Identity:	308/391 - (78%)
Similarity:	354/391 - (90%)	Gaps:	0/391 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 EDLSNVEFETSEDVEVIPTFNAMNLKEELLRGIYAYGFEKPSAIQQRSITPIVKGRDVIAQAQSG 73
            |.:.|||..|||||..:.:|..|||||:|||||||||:|.|||:|.|:|..|.||||||||||||
pombe     4 EIMENVELTTSEDVNAVSSFEEMNLKEDLLRGIYAYGYETPSAVQSRAIIQICKGRDVIAQAQSG 68

  Fly    74 TGKTATFSISILQSLDTTLRETQVLCLSPTRELAVQIQKVILALGDMMNVQCHVCIGGTNLGEDI 138
            |||||||||.||||:|.::|:||.|.||||||||||||.|:|||||.||||||.|||||::|.||
pombe    69 TGKTATFSIGILQSIDLSVRDTQALILSPTRELAVQIQNVVLALGDHMNVQCHACIGGTSVGNDI 133

  Fly   139 RKLDYGQHIVSGTPGRVFDMIKRRVLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVV 203
            :|||||||:||||||||.|||:||.||||.:|||:||||||:||:||||||||:||||||.||||
pombe   134 KKLDYGQHVVSGTPGRVTDMIRRRNLRTRNVKMLILDEADELLNQGFKEQIYDIYRYLPPGTQVV 198

  Fly   204 LISATLPHEILEMTSKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQA 268
            ::|||||.::||||:||.|:|:|||||||||||||:||:|:|||:||||||||||||||||||||
pombe   199 VVSATLPQDVLEMTNKFTTNPVRILVKRDELTLEGLKQYFIAVEKEEWKFDTLCDLYDTLTITQA 263

  Fly   269 VIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERDEIMKEFRAGQSRVLITTDVWARGIDVQQ 333
            |||||::|||||||||||||||||:||||:|||||||.||::||.|.|||||.||:|||||||||
pombe   264 VIFCNSRRKVDWLTEKMREANFTVTSMHGEMPQKERDAIMQDFRQGNSRVLICTDIWARGIDVQQ 328

  Fly   334 VSLVINYDLPNNRELYIHRIGRSGRFGRKGVAINFVKSDDIRILRDIEQYYSTQIDEMPMNVADL 398
            ||||||||||.|||.|||||||||||||||||||||.::|:||||||||||||.|||||||:.|:
pombe   329 VSLVINYDLPANRENYIHRIGRSGRFGRKGVAINFVTNEDVRILRDIEQYYSTVIDEMPMNIGDM 393

  Fly   399 I 399
            :
pombe   394 V 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7483	NP_649788.2	PTZ00424	4..399	CDD:185609	308/389 (79%)
SPAC1F5.10	NP_592863.1	PTZ00424	19..392	CDD:185609	298/372 (80%)
		DEADc	23..223	CDD:238167	152/199 (76%)
		HELICc	234..363	CDD:238034	111/128 (87%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	261	1.000	Domainoid score	I369
eggNOG	1	0.900	-	-		E2759_KOG0328
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5602
Inparanoid	1	1.050	641	1.000	Inparanoid score	I132
OMA	1	1.010	-	-		QHG53631
OrthoFinder	1	1.000	-	-		FOG0000304
OrthoInspector	1	1.000	-	-		oto101922
orthoMCL	1	0.900	-	-		OOG6_101114
Panther	1	1.100	-	-	LDO	PTHR47958
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R429
SonicParanoid	1	1.000	-	-		X250
TreeFam	1	0.960	-	-
	14	13.860