DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7483 and eif4a3.1

DIOPT Version :9

Sequence 1:	NP_649788.2	Gene:	CG7483 / 40987	FlyBaseID:	FBgn0037573	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_001107349.1	Gene:	eif4a3.1 / 100135173	XenbaseID:	XB-GENE-5773453	Length:	415	Species:	Xenopus tropicalis

Alignment Length:	391	Identity:	344/391 - (87%)
Similarity:	371/391 - (94%)	Gaps:	0/391 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 EDLSNVEFETSEDVEVIPTFNAMNLKEELLRGIYAYGFEKPSAIQQRSITPIVKGRDVIAQAQSG 73
            ||::.|||||||:|:|.|||:.|.|:|:|||||||||||||||||||:|..|:||||||||:|||
Frog    25 EDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSG 89

  Fly    74 TGKTATFSISILQSLDTTLRETQVLCLSPTRELAVQIQKVILALGDMMNVQCHVCIGGTNLGEDI 138
            |||||||.:|:||.||..:||||.|.|:||||||.|||||:|||||.||||||.||||||:||||
Frog    90 TGKTATFCVSVLQCLDIQVRETQALILAPTRELAGQIQKVLLALGDYMNVQCHACIGGTNVGEDI 154

  Fly   139 RKLDYGQHIVSGTPGRVFDMIKRRVLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVV 203
            ||||||||:|:||||||||||:||.|||||||||||||||||||||||||||||||||||||||.
Frog   155 RKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVC 219

  Fly   204 LISATLPHEILEMTSKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQA 268
            ||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||||||||
Frog   220 LISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQA 284

  Fly   269 VIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERDEIMKEFRAGQSRVLITTDVWARGIDVQQ 333
            ||||||||||||||||||||||||||||||||||||:.||||||:|.|||||:|||||||:||.|
Frog   285 VIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQ 349

  Fly   334 VSLVINYDLPNNRELYIHRIGRSGRFGRKGVAINFVKSDDIRILRDIEQYYSTQIDEMPMNVADL 398
            |||:|||||||||||||||||||||:|||||||||||:|||||||||||||||||||||||||||
Frog   350 VSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADL 414

  Fly   399 I 399
            |
Frog   415 I 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7483	NP_649788.2	PTZ00424	4..399	CDD:185609	342/389 (88%)
eif4a3.1	NP_001107349.1	PTZ00424	39..415	CDD:185609	332/375 (89%)
		Q motif	42..70		22/27 (81%)
		DEADc	44..244	CDD:238167	168/199 (84%)
		DEAD box. /evidence=ECO:0000305	191..194		2/2 (100%)
		HELICc	255..384	CDD:238034	119/128 (93%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	279	1.000	Domainoid score	I1674
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5602
Inparanoid	1	1.050	699	1.000	Inparanoid score	I660
OMA	1	1.010	-	-		QHG53631
OrthoDB	1	1.010	-	-		D321438at33208
OrthoFinder	1	1.000	-	-		FOG0000304
OrthoInspector	1	1.000	-	-		oto105072
Panther	1	1.100	-	-	LDO	PTHR47958
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R429
SonicParanoid	1	1.000	-	-		X250
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110