DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sgt1 and SGT1

DIOPT Version :9

Sequence 1:	NP_649783.2	Gene:	Sgt1 / 40982	FlyBaseID:	FBgn0265101	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	NP_014700.1	Gene:	SGT1 / 854222	SGDID:	S000005583	Length:	395	Species:	Saccharomyces cerevisiae

Alignment Length:	208	Identity:	67/208 - (32%)
Similarity:	103/208 - (49%)	Gaps:	37/208 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 DWYQSETKVVITVLLKNAVDKNYAVEI-----------TQKRVHMTADGYELDLKLLHPIVVERS 59
            |||||.|.|.|::...|..:....|.|           ...:|..:...::.:.||.|.:..:..
Yeast   188 DWYQSSTSVTISLFTVNLPESKEQVNIYISPNDRRTLSISYQVPKSGSEFQYNAKLSHEVDPKAV 252

  Fly    60 SYKAFSTKVEITLAKETGIRWENLEEAIV--AAPVKPKAKNWD---QLVSEE------------- 106
            |.|.|..|:||||:|....:|:.|||.|:  ::.:..:.||.|   :|:|.|
Yeast   253 SLKIFPKKLEITLSKIDSTQWKKLEEDILTESSRLSDEGKNSDSATRLLSAETASKERLSYPSSS 317

  Fly   107 -EKID------EKEAKGEA-ALTNLFKKIYSSSSPEVQKAMNKSFSESGGTVLSTNWNEVGKERV 163
             :|||      ::||..|| :..:.|:|:|:.:.|:.::||.|||.||.||.|||:|.:|.|..|
Yeast   318 KKKIDWSKLDIDEEADEEAGSADSFFQKLYAGADPDTKRAMMKSFIESNGTALSTDWEDVSKGTV 382

  Fly   164 TVKPPNGTEFREW 176
            ...||.|.|.:.|
Yeast   383 KTSPPEGMEPKHW 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sgt1	NP_649783.2	p23_CS_SGT1_like	6..84	CDD:107223	25/88 (28%)
Sgt1	NP_649783.2	SGS	97..176	CDD:282811	37/102 (36%)
SGT1	NP_014700.1	SGT1	10..395	CDD:227422	66/206 (32%)
		TPR repeat	37..77	CDD:276809
		TPR repeat	82..114	CDD:276809
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	64	1.000	Domainoid score	I2444
eggNOG	1	0.900	-	-		E1_COG5091
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	96	1.000	Inparanoid score	I1503
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004070
OrthoInspector	1	1.000	-	-		oto99038
orthoMCL	1	0.900	-	-		OOG6_102530
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R491
SonicParanoid	1	1.000	-	-		X2822
TreeFam	1	0.960	-	-
	11	10.750